Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Application of Generalized Partial Volume Estimation for Mutual Information based Registration of High Resolution SAR and Optical Imagery [PDF]
, 2008 Mutual information (MI) has proven its effectiveness for automated multimodal image registration for numerous remote sensing applications like image fusion.
Reinartz, Peter, Suri, Sahil
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Enhancement of traffic forecasting through graph neural network-based information fusion techniques [PDF]
To improve forecasting accuracy and capture complex interactions within transportation networks, information fusion approaches are crucial for traffic predictions based on graph neural networks (GNNs).
Kuldeep, SA +6 more
core +1 more source
Small target detection of floating objects in river channels based on improved YOLOv7
Scientific ReportsComputer vision-aided small target detection in moving streams, such as rivers/ roads, requires a fast-converging outcome as the frame requirements are high.
Weifeng Yang +13 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Implication of Culture : User Roles in Information Fusion for Enhanced Situational Understanding [PDF]
, 2009 Information Fusion coordinates large-volume data processing machines to address user needs. Users expect a situational picture to extend their ability of sensing events, movements, and activities.
Nilsson, Maria, +5 more
core
Considerations for enhancing situation assessment through multi-level fusion of hard and soft data [PDF]
, 2022 S.2133-2138This paper presents several lessons learned from the ongoing work of NATO IST-132 RTG-063 which is focused on data and information fusion incorporating structured and unstructured human generated information with device-generated data ...
Biermannn, J. +4 more
core
Node Deployment Algorithm for Underwater Sensor Networks Based on Connected Dominating Set
Sensors, 2016 Existing node deployment algorithms for underwater sensor networks are nearly unable to improve the network coverage rate under the premise of ensuring the full network connectivity and do not optimize the communication and move energy consumption during
Peng Jiang +4 more
doaj +1 more source