Results 41 to 50 of about 1,249,443 (317)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms of protection of information in computer networks and systems
Vojnotehnički Glasnik, 2011 Protocols of information protection in computer networks and systems are investigated. The basic types of threats of infringement of the protection arising from the use of computer networks are classified.
Sergey Petrovich Evseev +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Distributed Computations Environment Protection Using Artificial Immune Systems
Безопасность информационных технологий, 2011 In this article the authors describe possibility of artificial immune systems applying for distributed computations environment protection from definite types of malicious impacts.
A. V. Moiseev +2 more
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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Information Security Current Problems
Безопасность информационных технологий, 2010 The current problems of information security maintenance and information protection as one of the main factors for successful implementation of Strategy of the Information Society Development in Russia are analyzed.
A. A. Malyuk
doaj
On certain aspects of standardization and operating conditions of automated systems
Вестник Дагестанского государственного технического университета: Технические наукиObjective. In this paper, the main aspects of the operating conditions of the AS are considered, as well as the issues of standardization of the stages of the life cycle of the AS (creation, commissioning, maintenance, etc.) at the state level.
A. O. Efimov +4 more
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Online Personal Data Processing and EU Data Protection Reform. CEPS Task Force Report, April 2013 [PDF]
, 2013 This report sheds light on the fundamental questions and underlying tensions between current policy objectives, compliance strategies and global trends in online personal data processing, assessing the existing and future framework in terms of effective ...
Luchetta, Giacomo, Irion, Kristina
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source