Results 61 to 70 of about 4,412,712 (309)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Limitations of Passive Protection of Quantum Information

, 2009
The ability to protect quantum information from the effect of noise is one of the major goals of quantum information processing. In this article, we study limitations on the asymptotic stability of quantum information stored in passive N-qubit systems ...
Cirac, Ignacio, Kay, Alastair, Pastawski, Fernando, Schuch, Norbert   +3 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

MODEL OF THE PROCESS OF FUNCTIONING OF THE INFORMATION PROTECTION SYSTEM FROM UNAUTHORIZED ACCESS CREATED IN THE SOFTWARE ENVIRONMENT OF IMITATION MODELING "CPN TOOLS"

Вестник Дагестанского государственного технического университета: Технические науки, 2019
Objectives. At present, conducting a computational experiment on a system for protecting information from unauthorized access operated in an automated system is a time consuming process.
O. I. Bokova, I. G. Drovnikov, A. D. Popov, E. A. Rogozin   +3 more
doaj   +1 more source

Wastewater treatment plant inspection program, fiscal year 2006 and 2007 data report [PDF]

, 2008
This data report includes the results from Alachua County Environmental Protection Department’s inspections of wastewater treatment plants (WWTP) within Alachua County during the 2006 and 2007 fiscal years (October 2005 – September 2007).
Greco, Stacie
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Organization of the Own System of the Numeration for the Full Search Arguments at the Global Extremum Determination

Безопасность информационных технологий, 2011
The algorithm of the full search of the arguments for the conditional optimization of the multi-dimensional criterion is suggested. Determination consists of the serial numerical optimization several coefficients with the own numeration of the each ...
N. A. Kritsyna, Y. P. Kulyabichev, A. A. Malyuk, A. A. Sukhanov   +3 more
doaj  

Parents' involvement in care order decisions: a cross-country study of front-line practice [PDF]

, 2016
This article examines parents’ involvement in care order decision-making in four countries at one particular point in the care order process, namely when the child protection worker discusses with the parents his/her considerations regarding child ...
Alpert, Archard, Berrick, Berrick, Cantil-Sakauye, Child Welfare Act, Children Act, Corby, Crea, Dawson, De Godzinsky, DfE (Department for Education), Dickens, Duffy, Dumbrill, Eriksen, Estefan, Farrell, Fox Harding, Freymond, Gillies, Gladstone, Habermas, Hall, Huhtanen, Höjer, Ife, Kapp, Kemp, Klease, Lietz, Littell, Maxwell, McLendon, Meyer, Pearce, Rothstein, Skramstad, Smith, Soydan, Thomas, Virokannas   +41 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source