Results 61 to 70 of about 727,136 (175)

Multimedia Information Retrieval Model

open access: yes, 2009
Given a collection of multimedia documents, the goal of multimedia information retrieval (MIR) is to find the documents that are relevant to a user information need. A multimedia document is a complex information object, with components of different kinds, such as text, images, video and sound, all in digital form.
Meghini C, Sebastiani F, Straccia U
openaire   +5 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

reSearch : enhancing information retrieval with images [PDF]

open access: yes, 2009
Combining image and text search is an open research question. The main issues are what technologies to base this solution on, and what measures of relevance to employ. Our reSearch prototype mashes up papers indexed using information retrieval techniques
Goodfellow, Martin Hugh   +2 more
core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Word sense disambiguation and information retrieval [PDF]

open access: yes, 1914
It has often been thought that word sense ambiguity is a cause of poor performance in Information Retrieval (IR) systems. The belief is that if ambiguous words can be correctly disambiguated, IR performance will increase.
Sanderson, M.
core  

Information Retrieval - From Information Access to Contextual Retrieval

open access: yes, 2020
Information Retrieval (IR) deals with uncertainty and vagueness in in-formation systems. Uncertainty is caused by the problem of representing the semantics of text and other media, which cannot be done in a perfect way. On the other hands, information needs to be answered by IR systems are often vague and cannot be specified precisely, thus leading to ...
openaire   +2 more sources

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy