Results 61 to 70 of about 11,191,535 (322)

information science

, 2022
avaliação de palavras correlacionadas e autores da área de ciência da informação.
openaire   +2 more sources

Informing policy with science [PDF]

Science, 2017
We recently witnessed the peaceful—if controversial—transition of the United States presidency. As with any major change in federal government, the scientific community has concerns about new directions and priorities that may affect the way science is conducted, funded, and used in the United States and elsewhere.
openaire   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

The silent barrier: exploring data availability in Small Island Developing States

Revista Panamericana de Salud Pública
Objective. To quantify three aspects of data-related developmental progress across 57 Small Island Developing States (SIDS) recognized by the United Nations: statistical capacity measured using the Statistical Performance Indicators (SPI), data ...
Ian Richard Hambleton, Selvi Jeyaseelan
doaj   +1 more source

A Systematic Review of Nutrition Recommendation Systems: With Focus on Technical Aspects [PDF]

Journal of Biomedical Physics and Engineering, 2019
Background: Nutrition informatics has become a novel approach for registered dietitians to practice in this field and make a profit for health care.
Sh Abhari, Reza Safdari, K B Lankarani, L Azadbakht, Sh. R Niakan Kalhori, B Honarvar, S M Ayyoubzadeh, Z Karbasi, S Zakerabasali, Y Jalilpiran   +9 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Science, Information, and Power [PDF]

Science, 2007
![Figure][1] Now that the 110th united states congress is well settled in its seats, things are heating up—and the decisive recent report from the United Nations Intergovernmental Panel on Climate Change will help. Some of the early action is on the legislative front: The well-publicized “First Hundred Hours” of the new House Democratic majority ...
openaire   +3 more sources

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source