Results 71 to 80 of about 17,096,963 (292)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Information seeking behaviors in different study settings [PDF]
, 2019 Empirical studies of information seeking and retrieval (IS&R) behaviors that invite real users are generally conducted in two types of settings: laboratory setting and remote setting. In lab studies, participants are usually invited to a computer lab and
Liu, Jiqun, Wang, Yiwei, Shah, Chirag
core
Empirical Studies of Information Seeking Behaviors during Pandemics: A Review of Theoretical, Methodological Issues and Implications [PDF]
, 2020 This work-in-progress poster aims to report the results of a systematic review of empirical works of information-seeking behaviors during pandemics, with the focus on the most recent past pandemic, the 2009 H1N1 Influenza.
Hu, Zhan
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Information-seeking behavior in multilingual digital libraries: A study of the Saudi Digital Library [PDF]
, 2021 A few studies investigate the information-seeking behavior of multilingual digital libraries accessed by Arabic users for academic purposes. This dissertation investigates the user's information-seeking behavior of the Saudi Digital Library (SDL) in ...
Alsalmi, Hany
core
Smart Tools for Academic Information Seeking
Nordic Journal of Information Literacy in Higher Education, 2016 Systematic information seeking is an essential part of academic work. Research and information seeking go hand in hand, and both need planning. In the academic world you can hardly avoid the research plan, but you probably won’t hear that much about the ...
Eeva Koponen, Tiia Puputti
doaj +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Towards collaboration between information seeking and information retrieval
Information Research: An International Electronic Journal, 2005 Introduction. The conceptual framework of librarianship and information science has developed rapidly over the past decade with the prospect of application in other fields.
Carol C. Kuhlthau
doaj
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source