Results 71 to 80 of about 501,530 (217)

Factors Influencing Internet Health Information Seeking In India: An Application of the Comprehensive Model of Information Seeking

International Journal of Communication, 2021
With a basis of the comprehensive model of information seeking, a survey study was conducted in India that investigated the relationships among three categories of factors (demographics, health belief, and technology enabler) and three types of Internet ...
Shaohai Jiang, Iccha Basnyat, Piper Liping Liu   +2 more
doaj  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Active Data Selection and Information Seeking

Algorithms
Bayesian inference typically focuses upon two issues. The first is estimating the parameters of some model from data, and the second is quantifying the evidence for alternative hypotheses—formulated as alternative models.
Thomas Parr, Karl Friston, Peter Zeidman
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Information Seeking on the Web

Pakistan Journal of Information Management & Libraries
In the post-internet era, the Web has become a conventional Medium for information seeking. Due to the pervasive role of the web in information seeking many scholars have studied its different aspects.
Waseem Afzal
doaj  

Scholarly use of information: graduate students' information seeking behaviour

Information Research: An International Electronic Journal, 2006
Introduction. This study explored graduate students' information behaviour related to their process of inquiry and scholarly activities. Method. In depth, semi-structured interviews were conducted with one hundred graduate students representing all ...
C. George, A. Bright, T. Hurlbert, E.C. Linke, G. St. Clair, J. Stein   +5 more
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Active and passive information seeking by diabetic patients

Payesh, 2015
Objective (s): Health information seeking behavior describes how the individual search for and obtain health and medical information about health risks, diseases and illnesses, and health promotion activities.
Firoozeh Zare-Farashbandi, Anasik Lalazaryan, AliReza Rahimi, Akbar Hassanzadeh   +3 more
doaj