Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Examination is one of the common ways to evaluate the students’ cognitive levels in higher education institutions. Exam questions are labeled manually by educators in accordance with Bloom’s taxonomy cognitive domain. To ease the burden of the educators,
Anbuselvan Sangodiah +5 more
doaj
Assessing the Effects of Information System Quality and Relationship Quality on Continuance Intention in E-Tourism [PDF]
Ni Wayan Masri +4 more
openalex +1 more source
System combination with extra alignment information [PDF]
This paper provides the system description of the IHMM team of Dublin City University for our participation in the system combination task in the Second Workshop on Applying Machine Learning Techniques to Optimise the Division of Labour in Hybrid MT ...
Liu, Qun +3 more
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Sentiment analysis of reviews related to Unesco Global Geopark (UGG) Ciletuh Palabuhanratu on google maps using the naive bayes algorithm [PDF]
Ciletuh Geopark is part of the UNESCO Global Geopark Network. This study will analyze a tourist review of the Ciletuh Pelabuhan Ratu Geopark based on reviews on Google Maps.
Erfina Adhitia +2 more
doaj +1 more source
Inducing information extraction systems for new languages via cross-language projection [PDF]
Ellen Riloff +2 more
openalex +1 more source
The Usefulness of an Accounting Information System for Effective Organizational Performance
The aim of this study is to investigate usefulness of accounting information system (AIS) for effective organizational performance. AIS is the whole of the related components that are working together to collect, store and disseminate data for the ...
Siamak Nejadhosseini Soudani
semanticscholar +1 more source
Automated Data Management Information System (ADMIS) [PDF]
ADMIS stores and controls data and documents associated with manned space flight effort. System contains all data oriented toward a specific document; it is primary source of reports generated by the system.
Blackstone, C. +9 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

