A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Minutes: Senate Committee on Information Technologies: October 7, 2014
, 2014 University of Minnesota: Senate Committee on Information Technologies. (2014). Minutes: Senate Committee on Information Technologies: October 7, 2014.
University of Minnesota: Senate Committee on Information Technologies
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Minutes: Senate Committee on Information Technologies: March 6, 2012
, 2012 University of Minnesota: Senate Committee on Information Technologies. (2012). Minutes: Senate Committee on Information Technologies: March 6, 2012.
University of Minnesota: Senate Committee on Information Technologies
core
The JINR Tier1 Site Simulation for Research and Development Purposes
EPJ Web of Conferences, 2016 Distributed complex computing systems for data storage and processing are in common use in the majority of modern scientific centers. The design of such systems is usually based on recommendations obtained via a preliminary simulated model used and ...
Korenkov V. +6 more
doaj +1 more source
Editorial: Applications of geospatial information technologies and spatial statistics in health services research. [PDF]
Front Public Health, 2023 Song C, Wang X, Ge E, Shi X, Pan J.
europepmc +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Minutes: Senate Committee on Information Technologies: April 5, 2016
, 2016 University of Minnesota: Senate Committee on Information Technologies. (2016). Minutes: Senate Committee on Information Technologies: April 5, 2016.
University of Minnesota: Senate Committee on Information Technologies
core
Barriers and facilitators of using health information technologies by women: a scoping review. [PDF]
BMC Med Inform Decis Mak, 2023 Moulaei K, Moulaei R, Bahaadinbeigy K.
europepmc +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source