Results 91 to 100 of about 1,320,225 (265)

INFORMATION TECHNOLOGY AS A MEANS TO CAPTURE THE STUDENTS OF THE COURSE "METHODS OF "MATHEMATICS" EDUCATIONAL TEACHING FIELD"

open access: yesÌнформаційні технології в освіті, 2014
The paper presents an analysis of the concepts of "information technology", "Information Technologies in Education", "Information technology education", "computer technology", "New Information Technologies", "New Information Technologies in Education ...
Skvortsova S., Garan M.
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Intelligent Decision-Support System for Epidemiological Diagnostics. II. Information Technologies Development*, *. [PDF]

open access: yesCybern Syst Anal, 2022
Bazilevych KO   +4 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

LightIN: a versatile silicon-integrated photonic field programmable gate array with an intelligent configuration framework for next-generation AI clusters

open access: yesLight: Science & Applications
Artificial Intelligence models pose serious challenges to intensive computing and high-bandwidth communication for conventional electronic circuit-based computing clusters.
Ying Zhu   +16 more
doaj   +1 more source

Application of Blockchain Technologies and Smart Contracts for the Storage and Verification of Academic Transcripts in the Higher Education Systems

open access: yesInformation
This article discusses the practical implementation of a prototype academic transcript storage system based on blockchain technology and smart contracts.
Olga Ussatova   +5 more
doaj   +1 more source

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