Results 101 to 110 of about 1,316,855 (265)

Diabetes mellitus and inequalities in the equipment and use of information technologies as a socioeconomic determinant of health in Spain. [PDF]

Front Public Health, 2022
Bosch-Frigola I, Coca-Villalba F, Pérez-Lacasta MJ, Carles-Lavila M.   +3 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Intelligent Decision-Support System for Epidemiological Diagnostics. II. Information Technologies Development^*, ^*. [PDF]

Cybern Syst Anal, 2022
Bazilevych KO, Chumachenko DI, Hulianytskyi LF, Meniailov IS, Yakovlev SV.   +4 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

LightIN: a versatile silicon-integrated photonic field programmable gate array with an intelligent configuration framework for next-generation AI clusters

Light: Science & Applications
Artificial Intelligence models pose serious challenges to intensive computing and high-bandwidth communication for conventional electronic circuit-based computing clusters.
Ying Zhu, Yifan Liu, Xinyu Yang, Kailai Liu, Xin Hua, Ming Luo, Jia Liu, Siyao Chang, Jie Yan, Shengxiang Zhang, Miao Wu, Zhicheng Wang, Hongguang Zhang, Dong Wang, Daigao Chen, Xi Xiao, Shaohua Yu   +16 more
doaj   +1 more source

Progress toward contextualized, persuasive, and integrated consumer information technologies for health. [PDF]

J Am Med Inform Assoc, 2021
Bakken S.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

INFORMATION TECHNOLOGY AS A MEANS TO CAPTURE THE STUDENTS OF THE COURSE "METHODS OF "MATHEMATICS" EDUCATIONAL TEACHING FIELD"

Ìнформаційні технології в освіті, 2014
The paper presents an analysis of the concepts of "information technology", "Information Technologies in Education", "Information technology education", "computer technology", "New Information Technologies", "New Information Technologies in Education ...
Skvortsova S., Garan M.
doaj  

Twenty-five years of education and information technologies: Insights from a topic modeling based bibliometric analysis. [PDF]

Educ Inf Technol (Dordr), 2022
Ozyurt O, Ayaz A.
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source