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Minutes: Senate Committee on Information Technologies: February 7, 2017

open access: yes, 2017
University of Minnesota: Senate Committee on Information Technologies. (2017). Minutes: Senate Committee on Information Technologies: February 7, 2017.
University of Minnesota: Senate Committee on Information Technologies
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Minutes: Senate Committee on Information Technologies: October 22, 2018

open access: yes, 2018
University of Minnesota: Senate Committee on Information Technologies. (2018). Minutes: Senate Committee on Information Technologies: October 22, 2018.
University of Minnesota: Senate Committee on Information Technologies
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Minutes: Senate Committee on Information Technologies: March 5, 2013

open access: yes, 2013
University of Minnesota: Senate Committee on Information Technologies. (2013). Minutes: Senate Committee on Information Technologies: March 5, 2013.
University of Minnesota: Senate Committee on Information Technologies
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Minutes: Senate Committee on Information Technologies: February 7, 2012

open access: yes, 2012
University of Minnesota: Senate Committee on Information Technologies. (2012). Minutes: Senate Committee on Information Technologies: February 7, 2012.
University of Minnesota: Senate Committee on Information Technologies
core  

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