Results 121 to 130 of about 21,736,361 (314)

Minutes: Senate Committee on Information Technologies: February 14, 2022

open access: yes, 2022
In these minutes: IT Cyber Security; Data StorageUniversity of Minnesota: Senate Committee on Information Technologies. (2022). Minutes: Senate Committee on Information Technologies: February 14, 2022.
University of Minnesota: Senate Committee on Information Technologies
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Minutes: Senate Committee on Information Technologies: May 4, 2010

open access: yes, 2010
enhanced security of electronic devices; course management systemsUniversity of Minnesota: Senate Committee on Information Technologies. (2010). Minutes: Senate Committee on Information Technologies: May 4, 2010.
University of Minnesota: Senate Committee on Information Technologies
core  

LightIN: a versatile silicon-integrated photonic field programmable gate array with an intelligent configuration framework for next-generation AI clusters

open access: yesLight: Science & Applications
Artificial Intelligence models pose serious challenges to intensive computing and high-bandwidth communication for conventional electronic circuit-based computing clusters.
Ying Zhu   +16 more
doaj   +1 more source

Bridging Heterogeneous Agents: A Neuro-Symbolic Knowledge Transfer Approach

open access: yesTechnologies
This paper presents a neuro-symbolic approach for constructing distributed knowledge graphs to facilitate cooperation through communication among spatially proximate agents.
Artem Isakov   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Minutes: Senate Committee on Information Technologies: May 1, 2012

open access: yes, 2012
University of Minnesota: Senate Committee on Information Technologies. (2012). Minutes: Senate Committee on Information Technologies: May 1, 2012.
University of Minnesota: Senate Committee on Information Technologies
core  

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