Results 121 to 130 of about 4,686,984 (308)

Bridging Heterogeneous Agents: A Neuro-Symbolic Knowledge Transfer Approach

open access: yesTechnologies
This paper presents a neuro-symbolic approach for constructing distributed knowledge graphs to facilitate cooperation through communication among spatially proximate agents.
Artem Isakov   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Understanding How Vulnerable Populations Use Common Information and Communications Technologies (ICTs) to Access Health Care Information [PDF]

open access: yes, 2010
The goal of this study is to investigate patterns of internet access via computers and cellular telephones among the population being served by the Drexel University Eleventh (11th) Street Health Center (Here after, the Center) and to determine which ...
Dalrymple, Prudence W.   +2 more
core  

Ethics and Information Technology

open access: yesAustralasian Journal of Information Systems, 1997
The versatility and adaptability of information technology (IT) offer many potential benefits to society, its organisations and its citizens, but there are also associated risks. The social and ethical implications of this technology warrant special attention and have resulted in the creation of information ethics as a discrete area of study.
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

INFORMATION TECHNOLOGY AS A MEANS TO CAPTURE THE STUDENTS OF THE COURSE "METHODS OF "MATHEMATICS" EDUCATIONAL TEACHING FIELD"

open access: yesÌнформаційні технології в освіті, 2014
The paper presents an analysis of the concepts of "information technology", "Information Technologies in Education", "Information technology education", "computer technology", "New Information Technologies", "New Information Technologies in Education ...
Skvortsova S., Garan M.
doaj  

Third Revolution Digital Technology in Disaster Early Warning [PDF]

open access: yes, 2015
Networking societies with electronic based technologies can change social morphology, where key social structures and activities are organized around electronically processed information networks.
Amaratunga, Dilanthi   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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