Results 121 to 130 of about 23,523,530 (399)

Information Technology of Flash Learning English [PDF]

open access: yes, 2013
Pembelajaran untuk anak- anak sekarang ini sudah semakin maju. Namun di sekolah dasar masih menggunakan cara pembelajaran yang konvensional. Agaknya untuk saat seperti ini, cara itu dianggap kurang memadai.
Naval Pradiba, Setyo Harry
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Futur-forecast of developing library technology within forming a new information-technological paradigm

open access: yesБиблиосфера, 2014
The perspectives of information technologies development and their growing influence on society, as well as new requirements for developing strategies of libraries in the medium and longer term are considered.
N. S. Redkina
doaj  

Information technology in ophthalmology [PDF]

open access: yesBritish Journal of Ophthalmology, 1998
Ophthalmology and its adnexal disciplines are in the grip of an explosion in information technology (IT), as are most branches of medicine. Not only do we have a bewildering number of published (on paper that is) periodicals, textbooks, and society (or faculty or college) newsletters to sift, select, and assimilate information from, but we now also ...
openaire   +3 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Information Technology Innovation [PDF]

open access: yesThe Permanente Journal, 2008
“Innovation is what distinguishes between a leader and a follower” is a statement often attributed to Apple cofounder Steve Jobs. Nowhere is this saying truer than in the realm of information technology (IT), where the blistering pace of change can make even casual observers dizzy. Yet IT innovation can be a two-edged sword.
openaire   +3 more sources

Management of Information Technology in Indonesian Construction Industry [PDF]

open access: yes, 2004
This paper presents findings of a research project, which explores the current use ofinformation technology (IT) in the Indonesian construction Industry.
Pamulu, M. S. (Muhammad)
core  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Knowledge and information systems

open access: yesAgricultural Economics (AGRICECON), 2008
We can see that the today's management level of informations is not quite fully controlled in most businesses. Nowadays generation of information systems creates support for business processes with the aim of optimalization of these processes on the ...
E. Šilerová, L. Kučírková
doaj   +1 more source

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