Results 91 to 100 of about 22,001,787 (335)
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
IEEE Access, 2018 Massive multiple-input multiple-output (MIMO) is considered as a promising technique in wireless communication systems, which contains cellular base stations equipped with a very large number of antennas to serve multiple users.
Hieu Trong Dao, Sunghwan Kim
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Low-Complexity Gaussian Detection for MIMO Systems
Journal of Electrical and Computer Engineering, 2010 For single-carrier transmission over delay-spread multi-input multi-output (MIMO) channels, the computational complexity of the receiver is often considered as a bottleneck with respect to (w.r.t.) practical implementations.
Tianbin Wo, Peter Adam Hoeher
doaj +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Towards an Information Retrieval Theory of Everything [PDF]
, 2009 I present three well-known probabilistic models of information retrieval in tutorial style: The binary independence probabilistic model, the language modeling approach, and Google's page rank.
Hiemstra, Djoerd
core +2 more sources
Disjoint Pilot Power and Data Power Allocation in Multi-Cell Multi-User Massive MIMO Systems
IEEE Access, 2018 In this paper, we consider pilot and data power allocation in multi-cell multi-user massive multiple-input multiple-output (MIMO) systems to maximize the summation of spectral efficiency (sum SE).
Hieu Trong Dao, Sunghwan Kim
doaj +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
A Completion Time-Based Flow Scheduling for Inter-Data Center Traffic Optimization
IEEE Access, 2018 With the rise of cloud computing service, traffic in inter-data center wide area networks (inter-DC WANs) has been growing rapidly. Inter-data center traffic contains multitudinous data transfers that require to be accomplished within certain time ...
Wenbo Hu +3 more
doaj +1 more source