Results 111 to 120 of about 22,001,787 (335)
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Mimicking classical noise in ion channels by quantum decoherence
Scientific ReportsThe mechanism of selectivity in ion channels is still an open question in biology. Recent studies suggest that the selectivity filter may exhibit quantum coherence, which could help explain how ions are selected and conducted.
Mina Seifi +2 more
doaj +1 more source
IEEE AccessIn the medical domain, particularly in intensive care units (ICUs), the immense volume of patient data presents a significant challenge for clinicians, often resulting in the oversight of critical information or excessive time consumption in accessing it.
Ahmad Ayad +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Information Theory and Knowledge-Gathering [PDF]
It is assumed that human knowledge-building depends on a discrete sequential decision-making process subjected to a stochastic information transmitting environment.
Murphy, Roy E
core +1 more source
Fog Computing Meets URLLC: Energy Minimization of Task Partial Offloading for URLLC Services
IEEE AccessUltra-high reliability and ultra-low latency communication (URLLC) are critical challenges for upcoming 6G applications. Cloud computing and mobile edge computing (MEC) offer potential solutions but incur high deployment and maintenance costs due to ...
Chenhao Shi +3 more
doaj +1 more source