Results 11 to 20 of about 366 (127)

Identification of novel adipokines in the joint. Differential expression in healthy and osteoarthritis tissues. [PDF]

open access: yesPLoS ONE, 2015
OBJECTIVES:Emerging data suggest that several metabolic factors, released mainly by white adipose tissue (WAT) and joint tissues, and collectively named adipokines, might have a role in the pathophysiology of OA.
Javier Conde   +9 more
doaj   +1 more source

Exosomes from Kartogenin-Pretreated Infrapatellar Fat Pad Mesenchymal Stem Cells Enhance Chondrocyte Anabolism and Articular Cartilage Regeneration

open access: yesStem Cells International, 2021
Objective. To evaluate the effect of Kartogenin-pretreated exosomes derived from infrapatellar fat pad mesenchymal stem cells on chondrocyte in vitro and articular cartilage regeneration in vivo. Methods.
Jiahua Shao   +10 more
doaj   +1 more source

Recent Advance in Source, Property, Differentiation, and Applications of Infrapatellar Fat Pad Adipose-Derived Stem Cells

open access: yesStem Cells International, 2020
Infrapatellar fat pad (IPFP) can be easily obtained during knee surgery, which avoids the damage to patients for obtaining IPFP. Infrapatellar fat pad adipose-derived stem cells (IPFP-ASCs) are also called infrapatellar fat pad mesenchymal stem cells ...
Yu-chen Zhong   +3 more
doaj   +1 more source

The role of metabolic syndrome in the pathogenesis of knee osteoarthritis: a new view on the problem

open access: yesБюллетень сибирской медицины, 2021
Currently, numerous studies undeniably prove the influence of metabolic syndrome on osteoarthritis (OA) progression.In hyperlipidemia, free fatty acids abnormally accumulate in the cartilage tissue and provoke cell dysfunction and necrosis.
G. V. Poryadin   +3 more
doaj   +1 more source

Induction of osteoarthritis by injecting monosodium iodoacetate into the patellofemoral joint of an experimental rat model. [PDF]

open access: yesPLoS ONE, 2018
This study aimed to investigate the histopathological changes in the patellofemoral joint using a rat model of osteoarthritis that was induced using monosodium iodoacetate, and to establish a novel model of patellofemoral osteoarthritis in a rat model ...
Ikufumi Takahashi   +3 more
doaj   +1 more source

Magnetic Resonance Imaging of Hoffa’s Fat Pad

open access: yesTravmatologiâ i Ortopediâ Rossii, 2019
Background. Pathological changes in the size and structure of Hoffa’s fat pad can cause pain in the anterior section of the knee joint. Therefore, they should be diagnosed.
A. S. Stulov, A. N. Tarasov
doaj   +1 more source

Flexibility of infrapatellar fat pad affecting anterior knee pain 6 months after anterior cruciate ligament reconstruction with hamstring autograft

open access: yesScientific Reports, 2020
This study aimed to identify factors affecting anterior knee pain (AKP) after anterior cruciate ligament reconstruction (ACLR) with hamstring tendon autograft using ultrasonography.
Takashi Kitagawa   +7 more
doaj   +1 more source

Chemical composition of the infrapatellar fat pad of swine [PDF]

open access: yesJournal of Anatomy, 2004
AbstractThe porcine infrapatellar fat pad is a structure composed of adipocytes and adipose connective tissues. Limited information is available concerning its chemical composition. Samples of the fat pad collected from young hogs were dissected into two portions: a relatively hard core of the pad with cushioning properties (inner tissue), and a soft ...
Nakano, Takuo   +3 more
openaire   +3 more sources

Infrapatellar fat pad resection or preservation during total knee arthroplasty: a meta-analysis of randomized controlled trials

open access: yesJournal of Orthopaedic Surgery and Research, 2020
Background The infrapatellar fat pad (IPFP) or Hoffa’s fat pad is often resected during total knee arthroplasty in order to improve visibility. However, the management of the IPFP during total knee arthroplasty (TKA) is the subject of an ongoing debate ...
Changjiao Sun   +6 more
doaj   +1 more source

Epigenomic profiling of the infrapatellar fat pad in osteoarthritis

open access: yesHuman Molecular Genetics, 2023
Abstract Osteoarthritis is a prevalent, complex disease of the joints, and affects multiple intra-articular tissues. Here, we have examined genome-wide DNA methylation profiles of primary infrapatellar fat pad and matched blood samples from 70 osteoarthritis patients undergoing total knee replacement surgery.
Kreitmaier, P.   +5 more
openaire   +4 more sources

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