Results 41 to 50 of about 3,323 (171)

Genetic mapping of distal femoral, stifle, and tibial radiographic morphology in dogs with cranial cruciate ligament disease.

PLoS ONE, 2019
Cranial cruciate ligament disease (CCLD) is a complex trait. Ten measurements were made on orthogonal distal pelvic limb radiographs of 161 pure and mixed breed dogs with, and 55 without, cranial cruciate partial or complete ligament rupture.
Eleni Healey, Rachel J Murphy, Jessica J Hayward, Marta Castelhano, Adam R Boyko, Kei Hayashi, Ursula Krotscheck, Rory J Todhunter   +7 more
doaj   +1 more source

Infrapatellar fat pad area on knee MRI: does it correlate with the extent of knee osteoarthritis?

The Egyptian Journal of Radiology and Nuclear Medicine, 2021
Background Osteoarthritis (OA) of the knee joint is a common cause of chronic disability in older adults. During the past 10 years, the infrapatellar fat pad (IPFP) has emerged as a new player in the pathogenesis of knee OA.
Eman Ragab, Dena Serag
doaj   +1 more source

Newly identified intervertebral fat pad degenerates after intervertebral disc injury in a rat model of degeneration

Journal of Anatomy, EarlyView.
This study characterizes a newly‐described intervertebral fat pad (IVFP) anterior to rat IVDs, with evidence for its existence in mice and human IVDs as well. In rats, the IVFP gradually degenerated following IVD injury with changes in adipocyte size and fibrous tissue infiltration, suggesting it could play a functional role in IVD health and ...
Niklas H. Koehne, Irina Heggli, Agnieszka A. Karol, Alon Lai, Svenja Illien‐Jünger, Andrew C. Hecht, Nilsson Holguin, James C. Iatridis   +7 more
wiley   +1 more source

An emerging player in knee osteoarthritis: the infrapatellar fat pad [PDF]

Arthritis Research & Therapy, 2013
The role of inflammation in the development, progression, and clinical features of osteoarthritis has become an area of intense research in recent years. This led to the recognition of synovitis as an important source of inflammation in the joint and indicated that synovitis is intimately associated with pain and osteoarthritis progression.
Ioan-Facsinay, A., Kloppenburg, M.
openaire   +3 more sources

Characterization of the Ligamentum Mucosum in the Feline and Canine Stifle

Anatomia, Histologia, Embryologia, Volume 55, Issue 4, July 2026.
ABSTRACT In humans, the ligamentum mucosum (LM) is described as a ligamentous structure originating from the femoral intercondylar notch and inserting into the infrapatellar fat pad. Proposed clinical implications include knee stabilization, contribution to post‐operative revascularization of adjacent structures, and causation of anterior knee pain if ...
Nathan Thomas Ko, Elizabeth Moran Woodward   +1 more
wiley   +1 more source

Localized nodular synovitis of the infrapatellar fat pad

Indian Journal of Orthopaedics, 2013
We report a case of localized nodular synovitis of the infrapatellar fat pad impinging on the patellofemoral joint causing limitation of extension. Arthroscopy involved use of a superolateral portal because location of lesion hindered access via a conventional anterior portal.
Park, Jong-Hoon, Ro, Kyung-Han, Lee, Dae-Hee   +2 more
openaire   +3 more sources

Evaluation, Treatment, and Rehabilitation Implications of the Infrapatellar Fat Pad [PDF]

Sports Health: A Multidisciplinary Approach, 2015
Context: The infrapatellar fat pad (IFP) is in the anterior knee compartment and may be a major pain generator. Evidence Acquisition: A PubMed database search using the terms Hoffas fat pad, anterior interval, and infrapatellar fat pad
Hannon, Joseph, Bardenett, Sean, Singleton, Steven, Garrison, J. Craig   +3 more
openaire   +2 more sources

Serum Leptin Exacerbates Osteoarthritis by Promoting Subchondral Bone H‐Type Vessel Angiogenesis via Activation of the PI3K/AKT Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease closely associated with obesity. Adipokines secreted by adipose tissue play critical roles in disease progression. This study focuses on the adipokine leptin and investigates its relationship with knee osteoarthritis.
Ruifu Li, Zhao Xi, Shitong Luo, Jun Qin, Tao Liu, Jian Zhang   +5 more
wiley   +1 more source

Novel Biomaterial‐Based Synovial Fluid Analysis Reveals Protective microRNA Signatures in a Mouse Model of Acute Synovitis‐Driven Osteoarthritis

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
We successfully established a novel method for collecting synovial fluid in the murine knee joint using Tetra‐slime. Acute synovitis led to secondary cartilage degeneration in the early stage of OA, which might be attributed to the increase of MMP‐3, TNF‐α, and M1 macrophage activation in the synovium.
Kei Takahata, Kohei Arakawa, Takashi Yasuda, Saaya Enomoto, Takuya Katashima, Takamasa Sakai, Takanori Kokubun   +6 more
wiley   +1 more source

Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis

Exploration, Volume 6, Issue 3, June 2026.
Smart nanodelivery systems deliver therapeutic payloads across the cartilage matrix to ensure their sustained accumulation within chondrocytes at sites of injury. By targeting specific molecular targets and signaling pathways, these platforms modulate the pathological synovium‐cartilage axis to restore immunometabolic homeostasis and drive tissue ...
Qirui Zhao, Zhewen Mi, Shuya Liu, Shijun Liang, Linjia Peng, Zixuan Gao, Jiaming Li, Xiaoqing Lu, Zhiguang Ren, Yongjie Wan, Shengsheng Cui, Longlong Lu, Xiaoyang Gao, Tao Wang, Hui Liang, Furong Tian, de la Fuente Jesus M, Chong Xiang, Luyi Sun, Lichen Xiang, Daxiang Cui   +20 more
wiley   +1 more source