Intra-articular injection of mesenchymal stem cells (MSCs) is a promising strategy for osteoarthritis (OA) treatment. However, more and more studies reveal that the injected MSCs have poor adhesion, migration, and survival in the joint cavity.
Junjun Yang +15 more
doaj +1 more source
Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat. [PDF]
Autologous chondrocyte implantation (ACI) is a cell-based therapy that has been used clinically for over 20 years to treat cartilage injuries more efficiently in order to negate or delay the need for joint replacement surgery.
Garcia, J +5 more
core +4 more sources
The objective of this work was to assess the consequences of repeated intra-articular injection of monosodium urate (MSU) crystals with inflammasome priming by lipopolysaccharide (LPS) in order to simulate recurrent bouts of gout in rats.
Nathalie Accart +8 more
doaj +1 more source
Structure, ontogeny and evolution of the patellar tendon in emus (Dromaius novaehollandiae) and other palaeognath birds [PDF]
The patella (kneecap) exhibits multiple evolutionary origins in birds, mammals, and lizards, and is thought to increase the mechanical advantage of the knee extensor muscles.
Alexander +84 more
core +3 more sources
Photography of operative techniques and pathology during arthroscopy using a second arthroscope. [PDF]
The use of two arthroscopes is recommended to reduce the time needed for photography eliminating the need to remove video control from the main arthroscope, to record pathology and operative techniques for teaching without an additional light ...
Brown C H +3 more
core +2 more sources
A case of synovial lipomatosis with chronic synovitis presenting as acute knee pain [PDF]
Background: Synovial lipomatosis is a rare, benign, intra-articular lipoma-like lesion characterized by villous proliferation of the synovium, most commonly affecting the knee joint.
Sushma HM, Anoosha K, Vijay Shankar S, Amita K
core +1 more source
Possibility of using the infrapatellar (Hoffa’s) fat pad as a source of autologous stem cells
Stem cells are the basis for the creation of tissue-engineered structures in regenerative medicine. The most well-studied sources of stem cells are the embryo and bone marrow.
A. V. Korel +5 more
doaj +1 more source
Optimisation of osteogenic and chondrogenic differentiation potential using clonal mesenchymal stem cell populations derived from synovial fat pad [PDF]
Mesenchymal stem cells are a potential source of cells for the repair of bone and articular cartilage defects. We have previously demonstrated that the infrapatellar synovial fat pad is a rich source of mesenchymal stem cells and these cells are able to ...
Adesida, AB +4 more
core
The effects of experimental knee pain on lower limb corticospinal and motor cortex excitability [PDF]
Notable weakness of the quadriceps muscles is typically observed as a consequence of knee joint arthritis, knee surgery and knee injury. This is partly due to ongoing neural inhibition that prevents the central nervous system from fully activating the ...
Dalbeth, Nicola +4 more
core +4 more sources
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source

