Results 71 to 80 of about 819,497 (252)

Mitochondria‐Targeting Iron–Carbon Nanozymes Combat Hepatic Ischemia–Reperfusion Injury via the Dual Mechanisms of Respiratory Chain Remodeling and Pyroptosis Inhibition With MRI Monitoring

open access: yesAdvanced Science, EarlyView.
A mitochondrial‐targeted FeCD‐SS31 nanoplatform integrates ROS‐responsive SS31 release with cascade antioxidant Fe3O4/CDs cores to suppress both de novo and existing ROS. By restoring mitochondrial complex integrity and blocking caspase‐1–GSDMD‐N pyroptosis, it reduces neutrophil infiltration and alleviates hepatic ischemia–reperfusion injury, while ...
Qianying Du   +12 more
wiley   +1 more source

Synthesis of Gold Nanoparticles Using Cefopernazone as a Stabilizing Reagent and Its Application

open access: yesInternational Journal of Electrochemical Science, 2012
: Synthesis of gold nanoparticles using cefopernazone as a stabilizing reagent for a sensor was proposed. The gold nanoparticles were characterized by scanning electron microscopy, transmission electron microscopy, infrared spectrometry, ultraviolet ...
Xiaomeng Lü   +4 more
doaj   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

open access: yesAdvanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu   +11 more
wiley   +1 more source

Circadian changes in the composition of human milk macronutrients depending on pregnancy duration: a cross-sectional study

open access: yesInternational Breastfeeding Journal, 2020
Background The purpose of this study was to evaluate the circadian variation of human milk macronutrients and energy content depending upon pregnancy duration.
Ieva Jura Paulaviciene   +4 more
doaj   +1 more source

CircFAM65A/CANX Condensates Sequester FAM134B to Inhibit ER‐phagy and Suppress Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
The novel circRNA circFAM65A suppresses HCC progression. Mechanistically, circFAM65A drives CANX phase separation, which recruits FAM134B into condensates and blocks its interaction with LC3, thereby inhibiting ER‐phagy and HCC progression. Importantly, targeted circFAM65A delivery represents a potential therapeutic strategy for HCC.
Wenxiu Ru   +15 more
wiley   +1 more source

Optical gas sensing: a review [PDF]

open access: yes, 2013
The detection and measurement of gas concentrations using the characteristic optical absorption of the gas species is important for both understanding and monitoring a variety of phenomena from industrial processes to environmental change.
Hodgkinson, Jane, Tatam, Ralph P.
core   +1 more source

Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen   +12 more
wiley   +1 more source

Small Sample Infrared Spectrophotometry [PDF]

open access: yesReview of Scientific Instruments, 1955
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/70187/2/RSINAK-26-8-787-1 ...
openaire   +2 more sources

Overcoming the *H‐NOx Coupling Bottleneck via Palladium‐Enabled Relay Catalysis on CuCo2O4 Toward Ampere‐Level Nitrate‐to‐Ammonia

open access: yesAdvanced Science, EarlyView.
Pd‐doped hollow spiny CuCo2O4 microspheres deliver ampere‐level electrocatalytic nitrate to ammonia. Cu and Co sites undergo relay catalysis for sequential nitrate reduction, while Pd accelerates water dissociation to supply abundant active hydrogen (*H).
Yuhuan Cui   +8 more
wiley   +1 more source

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