Results 1 to 10 of about 2,239 (137)

Intravenous Treprostinil in Severe Inoperable Chronic Thromboembolic Pulmonary Hypertension Using Implantable Pumps—Single-Center Experience over More Than a Decade

Journal of Cardiovascular Development and Disease, 2023
The management of chronic thromboembolic pulmonary hypertension has significantly changed over the last decade with the availability of both specific therapies and interventional treatments.
Regina Steringer-Mascherbauer, Charlotte Huber, Uwe Fröschl, Dagmar Engleder, Reinhold Függer, Maria Lummersdorfer, Ralf Lenhard, Martin Martinek   +7 more
doaj   +1 more source

Advances and Challenges in IoT-Based Smart Drug Delivery Systems: A Comprehensive Review

Applied System Innovation, 2023
In the current era of technology, the internet of things (IoT) plays a vital role in smart drug delivery systems. It is an emerging field that offers promising solutions for improving the efficacy, safety, and patient compliance of drug therapies.
Amisha S. Raikar, Pramod Kumar, Gokuldas (Vedant) S. Raikar, Sandesh N. Somnache   +3 more
doaj   +1 more source

Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension

Pulmonary Circulation, 2020
Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro® pump (approved in Europe) has a fixed flow rate.
Manuel J. Richter, Satenik Harutyunova, Tom Bollmann, Simon Classen, Jan Fuge, Henning Gall, Felix Gerhardt, Hossein A. Ghofrani, Hartmut Gunkel, Ekkehard Grünig, Michael Halank, Alexander Heine, Hans Klose, Tobias J. Lange, Claus Neurohr, Kai Nickolaus, Christian F. Opitz, Stephan Rosenkranz, Hans-Jürgen Seyfarth, Khodr Tello, Ralf Ewert, Karen M. Olsson   +21 more
doaj   +1 more source

Analysis of Hepatic Artery Infusion (HAI) Chemotherapy Using Randomized Trials of Floxuridine (FUDR) for Colon Cancer Patients with Multiple Liver Metastases

Gastroenterology Research and Practice, 2022
Colorectal cancer (CRC) is one of the leading causes of cancer-related death, with most of the people who have the disease developing numerous liver metastases. Sixty percent of colon cancer patients have liver metastases.
Yuanming Li
doaj   +1 more source

Drug delivery: enabling technology for drug discovery and development.iPRECIO® Micro Infusion Pump: Programmable, refillable and implantable

Frontiers in Pharmacology, 2011
Successful drug delivery using implantable pumps may be found in over 12,500 published articles. Their versatility in delivering continuous infusion, intermittent or complex infusion protocols acutely or chronically has made them ubiquitous in drug ...
Tsung eTan, Stephanie W Watts, Robert Patrick Davis   +2 more
doaj   +1 more source

Long-term experience with implantable infusion pumps for intravenous treprostinil in pulmonary arterial hypertension—procedural safety and system-related complications

Pulmonary Circulation, 2020
Implantable pumps for intravenous treprostinil provide a promising option to overcome drawbacks of parenteral prostanoid administration with external pumps in pulmonary hypertension.
Regina Steringer-Mascherbauer, Maria Lummersdorfer, Reinhold Függer, Elisabeth Sigmund, Charlotte Huber, Dagmar Engleder, Uwe Fröschl, Josef Aichinger   +7 more
doaj   +1 more source

Anti-seizure therapy with a long-term, implanted intra-cerebroventricular delivery system for drug-resistant epilepsy: A first-in-man study

EClinicalMedicine, 2020
Background: A clinical feasibility study was undertaken at a single center of long-term intra-cerebroventricular drug delivery of the anti-seizure medication valproic acid, into the cerebrospinal fluid (CSF) in order to treat drug resistant focal ...
Mark Cook, Michael Murphy, Kristian Bulluss, Wendyl D'Souza, Chris Plummer, Emma Priest, Catherine Williams, Ashwini Sharan, Robert Fisher, Sharon Pincus, Eric Distad, Tom Anchordoquy, Dan Abrams   +12 more
doaj   +1 more source

Intrastriatal Memantine Infusion Dampens Levodopa-Induced Dyskinesia and Motor Deficits in a Mouse Model of Hemiparkinsonism

Frontiers in Neurology, 2019
Although the administration of dopamine precursor levodopa remains as the mainstay for the treatment of Parkinson's disease, long-term exposure to levodopa often causes a disabling complication, referred to as levodopa-induced dyskinesias. Therefore, the
Masatoshi Ogawa, Masatoshi Ogawa, Yu Zhou, Yu Zhou, Ryosuke Tsuji, Ryosuke Tsuji, Jiro Kasahara, Jiro Kasahara, Satoshi Goto, Satoshi Goto   +9 more
doaj   +1 more source

Intraarterial infusion chemotherapy for hepatic carcinoma using a totally implantable infusion pump [PDF]

Cancer, 1980
Intraarterial infusion chemotherapy has several theoretical advantage over conventional therapy for the treatment of unresectable malignancies. However, the catheter problems and patient restriction to the hospital associated with its use have resulted in infrequent application and a notable lack of progress in this field of oncology.
H, Buchwald, T B, Grage, P P, Vassilopoulos, T D, Rohde, R L, Varco, P J, Blackshear   +5 more
openaire   +2 more sources

Plain radiography in patients treated with intrathecal drug delivery using an implantable pump device

Insights into Imaging, 2017
Objectives Intrathecal drug administration using an implanted pump system is well established in intractable spasticity and pain. However, despite continuous advancements in manufacturing technology, adverse events related to the pump and catheter still ...
Elmar M. Delhaas, Biswadjiet S. Harhangi, Sander P. G. Frankema, Frank J. P. M. Huygen, Aad van der Lugt   +4 more
doaj   +1 more source