Results 211 to 220 of about 22,495 (292)

Challenges and opportunities in mitigating sarcoptic mange in wild South American camelids

The Journal of Wildlife Management, Volume 90, Issue 1, January 2026.
Wild South American camelids—vicuña and guanaco—face threats from sarcoptic mange, a contagious skin disease linked to severe population declines. Despite its impact, major gaps remain in understanding disease dynamics. This review summarizes current knowledge, identifies key data and management gaps, and outlines urgent actions for effective ...
Alynn M. Martin, Emiliana Isasi‐Catalá, Marília Salgado‐Caxito, Ana Gallegos, Leonardo Hostos‐Olivera, Paulo Colchao‐Claux, Steve Smith, L. Fabian Beltran‐Saavedra, Catherine Dougnac, Camila Germana, Mariana Montoya, Scott Carver, Paul C. Cross, Christian Walzer   +13 more
wiley   +1 more source

Personalized Parenteral Nutrition in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy: A Comprehensive Framework for Clinical Practice. [PDF]

J Pers Med
Sinatra N, Maniaci A, Cuttone G, Senussi Testa T, Tutino S, Paternò DS, Girombelli A, Ippati G, Caputo G, Sorbello M, La Via L.   +10 more
europepmc   +1 more source

Case Report: Compound Heterozygous SCNN1B Mutations Causing Pseudohypoaldosteronism Type 1B2 in Neonatal Twins

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
First Chinese neonatal cases of systemic PHA1B from novel compound‐heterozygous SCNN1B variants (c.585+2T>C; c.1544T>C) presented with life‐threatening hyperkalemia and hyponatremia unresponsive to steroids. Early genetic testing enabled targeted sodium supplementation and potassium‐binding therapy, normalizing electrolytes and underscoring SCNN1B ...
Zhiping Wang, Lijuan Long, Hongjuan Bi
wiley   +1 more source

Wernicke's encephalopathy due to total parenteral nutrition after jejunotomy: a case report. [PDF]

Ann Med Surg (Lond)
Zhu Z, He B, Jiang X, Bi X, Li C, Chu Y, Ma L.   +6 more
europepmc   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates, Michael Zientek, Kunal S. Taskar, Wen Lin, Tycho Heimbach, Stefan Willmann, Jessica Rehmel, Neil Parrott, Michael Hanley, Justine Badee, Yuan Chen, Susan Cole, Loeckie De Zwart, Sebastian Haertter, Rongrong Jiang, Masakatsu Kotsuma, Guiqing Liang, Yu‐Wei Lin, Jing Liu, Ying Ou, Juliane Rascher, Naveed A. Shaik, Jan Wahlstrom, Xiaofeng Wang, Guangqing Xiao, Ka Lai Yee, S. Y. Amy Cheung   +26 more
wiley   +1 more source

An Unexpected Manifestation of Non-islet Cell Tumor Hypoglycemia in Pancreatic Ductal Adenocarcinoma. [PDF]

Cureus
Alomar T, Kaur J, Horani M, Alomar S, Syoufi I.   +4 more
europepmc   +1 more source

Evaluation of the PK/PD Changes on MASLD‐Related Population—An Example From Simultaneous Acetaminophen Parent‐Metabolite PBPK/PD Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Patients with metabolic dysfunction‐associated steatotic liver disease (MASLD) may exhibit altered pharmacokinetics (PK) and pharmacodynamics (PD) of drugs compared with healthy populations. However, no physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model has been specifically developed for MASLD.
Shanshan Zhao, Lan Zhang
wiley   +1 more source

Extended Stability of Ascorbic Acid in Pediatric TPN Admixtures: The Role of Storage Temperature and Emulsion Integrity. [PDF]

Pharmaceutics
Chiczewski R, Sobol Ż, Pacholska A, Wątróbska-Świetlikowska D.   +3 more
europepmc   +1 more source

Evaluation of Hemodynamic Changes in Normovolemic Hypotensive Dogs Treated With Fluids Alone or in Combination With Ephedrine or Dobutamine

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Crystalloid fluids alone did not improve normovolemic hypotension in anesthetized dogs. Ephedrine or dobutamine reversed hemodynamic changes, but combining either with fluids offered no added benefit. Notably, dobutamine with fluids may have adverse effects. Larger studies are needed to assess differences between treatments.
Pardis Varzandeh, Bahman Mosallanejad, Hadi Imani Rastabi, Mohammad Razi Jalali, Seyed Reza Fatemi Tabatabaei   +4 more
wiley   +1 more source

Nutrition and Hydration at the End of Life in Intensive Care and General End-of-Life Care Settings: Balancing Clinical Evidence, Patient-Centered Care, and Ethical and Legal Principles-A Narrative Review. [PDF]

Nutrients
Stoian M, Stoian A, Bănescu C, Bandila SR, Babă DF, Azamfirei L.   +5 more
europepmc   +1 more source