Results 61 to 70 of about 22,495 (292)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Danger of co-administration ferric carboxymaltose and denosumab: hypophosphatemia

The Egyptian Journal of Internal Medicine
Both denosumab-induced hypocalcemia and ferric carboxymaltose infusion-related hypophosphatemia have been extensively documented. There are significant risks associated with combining ferric carboxymaltose parenteral infusions and denosumab, including ...
Aysun Seker, Nurdan Senturk Durmus
doaj   +1 more source

Whole-body protein kinetics in critically ill patients during 50 or 100% energy provision by enteral nutrition: A randomized cross-over study.

PLoS ONE, 2020
BackgroundEnteral nutrition (EN) is a ubiquitous intervention in ICU patients but there is uncertainty regarding the optimal dose, timing and importance for patient-centered outcomes during critical illness.
Martin Sundström Rehal, Felix Liebau, Jan Wernerman, Olav Rooyackers   +3 more
doaj   +1 more source

Exogenous Glucose Administration Impairs Glucose Tolerance and Pancreatic Insulin Secretion during Acute Sepsis in Non-Diabetic Mice [PDF]

, 2013
Objectives:The development of hyperglycemia and the use of early parenteral feeding are associated with poor outcomes in critically ill patients. We therefore examined the impact of exogenous glucose administration on the integrated metabolic function of
Adolfo Garcia-Ocana, AO Agwunobi, Baobo Zou, Bryan J. McVerry, Charles C Caldwell, Christopher P. O’Donnell, Darko Stefanovski, DC Angus, DC Frankenfield, FM Brunkhorst, G Van den Berghe, G Van den Berghe, G Vila, JE Ayala, JF Patiño, JG Heuer, JL Berk, JM Naylor, K Maedler, Lanping Guo, Laura C. Alonso, LC Alonso, LC Alonso, ME Woodske, MP Casaer, MR Losser, NS Sauter, PE Marik, R Krogh-Madsen, RN Bergman, S Finfer, S Hagiwara, SJ Finney, Srikanth Singamsetty, VK Mehta, Y Wei, Yoshio Watanabe   +36 more
core   +4 more sources

Aloe vera Tannin Ameliorates Fructose‐Induced Dyslipidaemia and Oxidative Stress in Wistar Rats

Food Chemistry International, EarlyView.
Aloe vera tannin (AVT) significantly enhances liver reduced glutathione and superoxide dismutase activities in rats. Fructose consumption creates dyslipidaemia in rats by significantly increasing serum cholesterol and LDL levels. AVT prevented fructose‐induced dyslipidaemia in rats by controlling the lipid profile. AVT did not affect liver, hippocampus
Nathan Isaac Dibal, Fatimah Buba, Luteino Lorna Hamman, Sunday Joseph Manye, Zainab Abubakar Abdullahi, Nafisah Ibrahim Umar, Usman Aliyu, Abdulhamid Mahmud, Naim Muazu, Yahaya Musa Dugje, Patience Friday, Yakubu Garba Bilyaminu, Hadiza Ali Makinta   +12 more
wiley   +1 more source

Tocotrienols: A Review From Source to Therapeutic Applications

Food Frontiers, EarlyView.
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño, Nidia Casas‐Forero, Andres‐Felipe Garzón‐Méndez, Dalí‐Aleixandra Rojas‐Díaz, Mary‐Luz Olivares‐Tenorio, Hernan‐Mauricio Romero, Jesús‐Alberto García‐Núñez   +6 more
wiley   +1 more source

THE COMBINATION OF ANNULAR PANCREAS, PARASTERNAL DIAPHRAGMATIC HERNIA IN A NEWBORN WITH DOWN SYNDROME

Вестник хирургии имени И.И. Грекова, 2018
Malformations  and  premature birth are  the  most  important  causes of chronic  diseases, disability and  mortality in childhood. Help  for  children   with  malformations  is  often  needed immediately   after  birth.  WHO  determines heart   defects, 
M. A. Aksel’rov, V. A. Emel’janov
doaj   +1 more source

Enteral feeding pumps: efficacy, safety, and patient acceptability. [PDF]

, 2014
Enteral feeding is a long established practice across pediatric and adult populations, to enhance nutritional intake and prevent malnutrition. Despite recognition of the importance of nutrition within the modern health agenda, evaluation of the efficacy ...
King, L, White, H
core   +2 more sources

Cetuximab Hypersensitivity in the Setting of Asymptomatic Alpha‐Gal Sensitization

Head &Neck, EarlyView.
ABSTRACT Background Alpha‐gal syndrome is an allergic condition resulting from the bite of the Lonestar tick in the southeastern US that leads to sensitization to mammalian products containing the oligosaccharide galactose‐alpha‐1,3‐galactose (alpha‐gal).
Alexander G. Emerson, Lindsay Mundy, Barbara A. Murphy, Cosby A. Stone   +3 more
wiley   +1 more source

Infusión prolongada de ketamina y pruebas de función hepática [PDF]

Revista Chilena de Anestesia, 2023
Yerlin Andrés Colina Vargas, William Henry Joaqui Tapia, Cristina Posada Giraldo, Santiago Barrientos Henao, Cristian Vera Marín, José Julián Aristizábal   +5 more
doaj   +1 more source