Novel surgical approach for intraventricular cerliponase alfa enzyme replacement therapy via central venous access device (CVAD) port in neuronal ceroid lipofuscinosis type 2 (CLN2) disease. [PDF]
Boop S+8 more
europepmc +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Long-term maintenance of remission with spacing of rituximab infusions based on the individualised patient risk profile in ANCA-associated vasculitis: a pilot study. [PDF]
Bartoletti A+4 more
europepmc +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
Retrospective Cohort Analysis of 1-Hour Infliximab Infusions in Pediatric Patients. [PDF]
Goodrich D+4 more
europepmc +1 more source
Chemotherapy of retinoblastoma.Intracayotid arterial infusion and isolation head and neck perfmion—tracer studies [PDF]
George A. Hyman+3 more
openalex +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
Paternal heroin self-administration in rats increases drug-seeking behavior in male offspring via miR-19b downregulation in the nucleus accumbens. [PDF]
Gao W+10 more
europepmc +1 more source
Stimulation of insulin secretion by infusion of free fatty acids [PDF]
Stephen R. Crespin+2 more
openalex +1 more source
Meta‐analysis: rapid infliximab infusions are safe
H. C. Neef+2 more
semanticscholar +1 more source