Results 211 to 220 of about 636,834 (344)

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Retrospective Cohort Analysis of 1-Hour Infliximab Infusions in Pediatric Patients. [PDF]

open access: yesJ Pediatr Pharmacol Ther
Goodrich D   +4 more
europepmc   +1 more source

Chemotherapy of retinoblastoma.Intracayotid arterial infusion and isolation head and neck perfmion—tracer studies [PDF]

open access: bronze, 1964
George A. Hyman   +3 more
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Stimulation of insulin secretion by infusion of free fatty acids [PDF]

open access: bronze, 1969
Stephen R. Crespin   +2 more
openalex   +1 more source

Meta‐analysis: rapid infliximab infusions are safe

open access: yesAlimentary Pharmacology and Therapeutics, 2013
H. C. Neef   +2 more
semanticscholar   +1 more source

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