Results 211 to 220 of about 636,834 (344)

Novel surgical approach for intraventricular cerliponase alfa enzyme replacement therapy via central venous access device (CVAD) port in neuronal ceroid lipofuscinosis type 2 (CLN2) disease. [PDF]

Childs Nerv Syst
Boop S, Nistal D, Barrios-Anderson A, Cherny WB, Chang IJ, Shelkowitz E, Kho T, Goldstein HE, Hauptman J.   +8 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Long-term maintenance of remission with spacing of rituximab infusions based on the individualised patient risk profile in ANCA-associated vasculitis: a pilot study. [PDF]

RMD Open
Bartoletti A, Milanesi A, Monti S, Montecucco C, Delvino P.   +4 more
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Retrospective Cohort Analysis of 1-Hour Infliximab Infusions in Pediatric Patients. [PDF]

J Pediatr Pharmacol Ther
Goodrich D, George A, Stein J, Koziol R, Costigan B.   +4 more
europepmc   +1 more source

Chemotherapy of retinoblastoma.Intracayotid arterial infusion and isolation head and neck perfmion—tracer studies [PDF]

, 1964
George A. Hyman, C Feind, Harold F. Spalter, M.P. Finkel   +3 more
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Paternal heroin self-administration in rats increases drug-seeking behavior in male offspring via miR-19b downregulation in the nucleus accumbens. [PDF]

Neuropsychopharmacology
Gao W, Wang T, Cui J, Huang N, Fan G, Pan T, Jiang C, Wang F, Liu X, Ma L, Le Q.   +10 more
europepmc   +1 more source

Stimulation of insulin secretion by infusion of free fatty acids [PDF]

, 1969
Stephen R. Crespin, William B. Greenough, Daniel Steinberg   +2 more
openalex   +1 more source

Meta‐analysis: rapid infliximab infusions are safe

Alimentary Pharmacology and Therapeutics, 2013
H. C. Neef, M. P. Riebschleger, Jeremy Adler   +2 more
semanticscholar   +1 more source