Results 211 to 220 of about 849,946 (335)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Economic assessment of treated feed with certain ingredients in crossbred dairy cattle under sub- tropical conditions [PDF]

, 2020
Dhawal Kant Yadav, Panch Kishor Bharti, Amit Kumar Singh, Manmohan Singh Rajput, Gyanendra Kumar Gaur, Putan Singh   +5 more
openalex  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Prescription of vitamin D in neonates and infants under one year of age in Spain: an eight-year observational study. [PDF]

BMC Prim Care
Jorge-Novoa C, Lizano-Díez I, Viñas-Bastart M, Braza AJ, Muñoz-Cortés M, Figueiredo-Escribá C, Mariño EL, Modamio P.   +7 more
europepmc   +1 more source

RIFM fragrance ingredient safety assessment, p-isobutyl-α-methyl hydrocinnamaldehyde, CAS Registry Number 6658-48-6

, 2020
A.M. Api, D. Belsito, S. Biserta, D. Botelho, M. Bruze, G.A. Burton, J. Buschmann, M.A. Cancellieri, M.L. Dagli, M. Date, W. Dekant, C. Deodhar, A.D. Fryer, S. Gadhia, L. Jones, K. Joshi, A. Lapczynski, M. Lavelle, D.C. Liebler, M. Na, D. O’Brien, A. Patel, T.M. Penning, G. Ritacco, F. Rodríguez-Ropero, J. Romine, N. Sadekar, D. Salvito, T.W. Schultz, F. Siddiqi, I.G. Sipes, G. Sullivan, Y. Thakkar, Y. Tokura, S. Tsang   +34 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Manufacturing Supply Chains and Imports in the ADHD Drug Shortage.

JAMA Health Forum
Currie J, Malinovskaya A.
europepmc   +1 more source

TCMToxDB: a comprehensive database for the toxicological analysis of traditional Chinese medicines. [PDF]

Database (Oxford)
Zhu Y, Fang L, Miao Y, Ma L, Sun R, Mao Y, Guo W, Wang J, Yu G.   +8 more
europepmc   +1 more source

Valorização de resíduos da indústria agro-alimentar através do desenvolvimento de ingredientes funcionais e nutracêuticos

, 2010
Pedro Figueiredo
openalex   +1 more source

Acceptability of Leaf-Enriched Buns Using Kangkong (Ipomoea Aquatica), and Kulitis (Amaranthus Viridis) Leaves as Functional Ingredients for Calamity Situations

Frezza B. Palattao
openalex   +1 more source