Results 41 to 50 of about 94,856 (286)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Primary data, claims data, and linked data in observational research: the case of COPD in Germany

Respiratory Research, 2018
Background Real-world evidence (RWE) can inform patient management decisions, but RWE studies are associated with limitations. Linkage of different RWE data types could address such limitations by enriching data and improving scientific quality.
Sabrina Mueller, Fraence Gottschalk, Antje Groth, Wilhelmine Meeraus, Maurice Driessen, Thomas Kohlmann, Thomas Wilke   +6 more
doaj   +1 more source

Identifying car ingress movement strategies before and after total knee replacement [PDF]

, 2020
Background: Post-operative performance of knee bearings is typically assessed in activities of daily living by means of motion capture. Biomechanical studies predominantly explore common tasks such as walking, standing and stair climbing, while ...
Clarke, Jon, Ewen, Alistair, Govind, Cheral, Jeldi, Artaban, Komaris, Dimitrios Sokratis, Murphy, Andrew, Riches, Philip   +6 more
core   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A Two-Dimensional Infrared Map of the Extrasolar Planet HD 189733b

, 2012
We derive the first secondary eclipse map of an exoplanet, HD 189733b, based on Spitzer IRAC 8 micron data. We develop two complementary techniques for deriving the two dimensional planet intensity: regularized slice mapping and spherical harmonic ...
Agol, Burrows, Charbonneau, Cooper, Cowan, Crossfield, Deming, Dobbs-Dixon, Fabrycky, Górski, Horne, Knutson, Knutson, Langton, Lanza, Rauscher, Rauscher, Showman, Showman, Showman, Williams, Young, Young   +22 more
core   +1 more source

A novel ingress node design for video streaming over optical burst switching networks [PDF]

, 2011
This paper introduces a novel ingress node design which takes advantage of video data partitioning in order to deliver enhanced video streaming quality when using H.264/AVC codec over optical burst switching networks.
Belbekkouche, Chen, D. K. Hunter, D. Simeonidou, Duser, G. Zervas, Liao, Park, S. Askar, Venkatesh   +9 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Long-term Influence of Concrete Surface and Crack Orientation on Self-healing and Ingress in Cracks – Field Observations

Nordic Concrete Research, 2018
This paper presents results from investigations on the long-term influence of concrete surface and crack orientation on ingress in cracks. Five reinforced concrete structures from Norway exposed to either de-icing salts or seawater have been investigated.
Danner Tobias, Geiker Mette Rica
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Matching‐adjusted indirect comparison of efficacy and safety of bortezomib, thalidomide, and dexamethasone (VTd) as per label compared with modified VTd dosing schedules in patients with newly diagnosed multiple myeloma who are transplant eligible

eJHaem, 2020
Background The combination of bortezomib, thalidomide, and dexamethasone (VTd) is a standard of care for transplant‐eligible patients with newly diagnosed multiple myeloma (NDMM). Although approved labeling for VTd includes an escalating thalidomide dose
Pieter Sonneveld, María‐Victoria Mateos, Adrian Alegre, Thierry Facon, Cyrille Hulin, Mahmoud Hashim, Talitha Vincken, Tobias Kampfenkel, Sarah Cote, Jianming He, Annette Lam, Philippe Moreau   +11 more
doaj   +1 more source