Results 221 to 230 of about 64,020 (238)

Machine learning assisted methods for the identification of low toxicity inhibitors of Enoyl-Acyl Carrier Protein Reductase (InhA)

Comput. Biol. Chem.
Tuberculosis (TB) is one of the life-threatening infectious diseases with prehistoric origins and occurs in almost all habitable parts of the world. TB mainly affects the lungs, and its etiological agent is Mycobacterium tuberculosis (Mtb). In 2022, more
R. Chikhale, H. T. M. Abdelghani, Hemchandra Deka, A. Pawar, Pritee Chunarkar Patil, Shovonlal Bhowmick   +5 more
semanticscholar   +1 more source

Development of Mycobacterium tuberculosis Enoyl Acyl Reductase (InhA) Inhibitors: A Mini-Review.

Mini-Reviews in Medical Chemistry
This review article delves into the critical role of Enoyl acyl carrier protein Reductase (InhA; ENR), a vital enzyme in the NADH-dependent acyl carrier protein reductase family, emphasizing its significance in fatty acid synthesis and, more specifically,
N. Tailor, Geeta Deswal, Kumar Guarve, A. Grewal   +3 more
semanticscholar   +1 more source

Virtual screening assisted discovery of novel natural products to inhibit the catalytic mechanism of Mycobacterium tuberculosis InhA

, 2021
The pandemic prevalence of tuberculosis (TB) caused by increasing drug-resistant Mycobacterium tuberculosis (Mtb) strains has posed severe global health threats.
Manikandan Jayaraman, L. Loganathan, K. Muthusamy, K. Ramadas   +3 more
semanticscholar   +1 more source

Klinische Erfahrungen mit INHA-PAS

Beiträge zur Klinik der Tuberkulose und spezifischen Tuberkulose-Forschung, 1956
Es wird uber klinische Erfahrungen an 54 Fallen mit INHA-PAS behandelter Lungentuberkulose berichtet. Das Praparat wird der Kombination INH und PAS mindestens gleichgestellt, was den therapeutischen Effekt angeht. Es wird die Uberlegenheit des Praparates in Hinsicht auf Vertraglichkeit, Dosierbarkeit und Wirtschaftlichkeit betont.
openaire   +1 more source

HISTORY OF INHA INTERNATIONAL UNIVERSITY

INHA International University (IIU) is a renowned higher education institution with a rich history spanning several decades. Originally established as a specialized university focused on maritime education, IIU has evolved into a comprehensive university offering a wide range of academic programs.
openaire   +1 more source

Can inhA mutation predict ethionamide resistance?

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2013
A tertiary care centre in Mumbai, India.To estimate the extent of association between inhA mutant isoniazid (INH) resistant strains and ethionamide (ETH) resistance.A total of 140 clinical isolates processed for INH and ETH phenotypic drug susceptibility testing, and molecularly processed with the line-probe assay (LPA) Genotype® MTBDRplus, were ...
V, Vadwai, K, Ajbani, M, Jose, V P, Vineeth, C, Nikam, M, Deshmukh, A, Shetty, R, Soman, C, Rodrigues   +8 more
openaire   +1 more source

Discovery of novel and potent InhA direct inhibitors by ensemble docking-based virtual screening and biological assays

Journal of Computer-Aided Molecular Design, 2023
Qianqian Zhang, Jianting Han, Yongchang Zhu, Fansen Yu, Xiaopeng Hu, H. H. Tong, Huanxiang Liu   +6 more
semanticscholar   +1 more source

Mycobacterium enoyl acyl carrier protein reductase (InhA): A key target for antitubercular drug discovery.

Bioorganic chemistry (Print), 2021
M. Prasad, R. Bhole, P. Khedekar, R. Chikhale   +3 more
semanticscholar   +1 more source

Daniel Arasse (Paris, INHA, 2006)

2010
International ...
openaire   +1 more source

I. K. Inha Kalevalan laulumailta

1912
Kirja-arvioInha, I.
openaire   +1 more source