Results 61 to 70 of about 64,020 (238)
Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
Advanced Science, EarlyView.The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source
PLoS ONE, 2015 Examination of InhA mutants I16T, I21V, I47T, S94A, and I95P showed that direct and water mediated H-bond interactions between NADH and binding site residues reduced drastically.
Vivek Kumar, M Elizabeth Sobhia
doaj +1 more source
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance. [PDF]
, 2018 Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex evolution of antimicrobial resistance (AMR). Accordingly, the many publicly available datasets describing its AMR characteristics demand disparate data-type analyses ...
Anand, Amitesh +11 more
core +2 more sources
ChemistrySelectTuberculosis (TB) caused by the Mycobacterium tuberculosis (MTB) pathogen is a serious contagious illness that endangers the public's health. However, TB is treatable but due to the result of ineffective and protracted medication, MDR‐MTB and XDR‐MTB ...
Poonam Gupta +4 more
semanticscholar +1 more source
INHEALTH : INDONESIAN HEALTH JOURNAL, 2022 TB adalah penyakit menular yang disebabkan M.tuberculosis. Penemuan kandidat obat baru dalam penanggulangan TB sangat penting karena beberapa obat TB sudah tidak mempan lagi. Caesalpina sappanis Lignum dapat menjadi kandidat dalam pengembangan obat baru
A.Wahyu Suryadi Ningrat
semanticscholar +1 more source
First triclosan-based macrocyclic inhibitors of InhA enzyme
Bioorganic Chemistry, 2020 Two macrocyclic derivatives based on the triclosan frame were designed and synthesized as inhibitors of Mycobacterium tuberculosis InhA enzyme. One of the two molecules M02 displayed promising inhibitory activity against InhA enzyme with an IC50 of 4.7 μM.
Rodriguez, Frédéric +5 more
openaire +5 more sources
Unraveling the High‐Rate Electrochemical Kinetics of CuSbS2 for Sodium Storage
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.This study investigates CuSbS2 as a high‐performance anode material for sodium‐ion batteries. CuSbS2 shows improved capacity retention and rate performance compared to Sb2S3. Various electrochemical techniques, including DRT from in situ EIS and GITT, confirm its enhanced reaction kinetics, underscoring the potential of bimetallic sulfides for next ...
Youngho Jin +9 more
wiley +1 more source
Backpropagation Artificial Neural Network To Detect Hyperthermic Seizures In Rats [PDF]
, 2002 A three-layered feed-forward back-propagation Artificial Neural Network was used to classify the seizure episodes in rats. Seizure patterns were induced by subjecting anesthetized rats to a Biological Oxygen Demand incubator at 45-47ºC for 30 to 60 ...
Sinha, Mr Rakesh Kumar
core
Why does the recently proposed simple empirical formula for the lowest excitation energies work so well? [PDF]
, 2008 It has recently been shown that a simple empirical formula, in terms of the mass number and the valence nucleon numbers, is able to describe the main trends of the lowest excitation energies of the natural parity even multipole states up to $10^+$ in ...
Cha, Dongwoo +2 more
core +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.A first‐of‐its‐kind review benchmarks three solar methane valorization pathways with unified performance metrics for clean fuel production. Meeting global climate targets and sustainable energy demands requires carbon‐neutral fuels and innovative conversion pathways.
Muhammad Abdulmoez +3 more
wiley +1 more source