Results 131 to 140 of about 43,739 (310)

On the emergence of criticality for inhalation-driven particle deposition in the anatomical upper airway [PDF]

open access: yesarXiv
Inhalation directs air through a defined pathway, initiating from nostrils, moving through the main nasal cavity, past the pharynx and trachea, and culminating in the lungs. Inhaled particles, of a range of sizes, are ferried by this incoming air but are filtered and trapped by upper airway structures to protect the delicate lower respiratory system ...
arxiv  

Identifying the optimal dose of cannabidiol by intrabuccal administration in Kramnik (C3HeB/FeJ) mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo   +4 more
wiley   +1 more source

Description of unilateral kidney embolism and contralateral nephrectomy as a less invasive remnant kidney model in cats; a proof‐of‐concept study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Unilateral, minimally invasive, renal arterial embolization and delayed contralateral nephrectomy was described in cats as a novel remnant kidney model of chronic kidney disease using two doses of embolic particles. Renal function declined and characteristic histopathological markers of kidney disease were present 6 months after the embolism procedure.
Chad W. Schmiedt   +7 more
wiley   +1 more source

Dose N2O Cause Paradoxical Reaction in Response to Noxious Stimulants During Inhalation Induction of Anesthesia in Pediatrics?

open access: yesمجله دانشکده پزشکی اصفهان, 2009
Background: Bispectral Index is one of the qualitative methods of measuring of sedation and depth of anesthesia. In a few studies appeared a paradoxical effect of N2O on BIS in adults.
Mohamad Golparvar, Alireza Koosha
doaj  

Improved husbandry measures to enhance reproducibility of wound healing studies in the Leprdb/db mouse

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Though the Leprdb/db mouse is a common and well‐studied model of type II diabetes mellitus, there are a few specific guidelines for its husbandry, and wound complications are common. We present a modified husbandry approach for the Leprdb/db mouse that includes increased cage size, decreased housing density, and more frequent cage changes.
May Barakat   +6 more
wiley   +1 more source

A case of disseminated intravascular coagulation of sepsis that caused extreme‐thrombocytopenia treated at a remote‐island‐hospital

open access: yesJournal of General and Family Medicine, Volume 24, Issue 1, Page 50-53, January 2023., 2023
A 66‐year‐old male had urinary tract infection by Escherichia coli, followed by septic shock and DIC rapidly just two days after the onset. He was treated and recovered in three weeks without any massive bleeding at a remote‐island‐hospital. Gram‐staining and immediate insertion of CV are essential techniques to care severe infections even in remote ...
Kazuyoshi Takeshita   +3 more
wiley   +1 more source

Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin   +9 more
wiley   +1 more source

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