Phytotherapy Research, EarlyView.Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan +8 more
wiley +1 more source
General anesthesia and depth of anesthesia (DoA) evaluation methods in laboratory animals: a comprehensive review. [PDF]
Vet Res CommunAltınoluk T, Kazdağlı H.
europepmc +1 more source
Phytotherapy Research, EarlyView.Under iron overload conditions, curcumin inhibits cellular senescence and promotes osteogenic differentiation by activating the NRF2/GPX4 signaling pathway in bone marrow mesenchymal stem cells (BMSCs), thereby preventing the onset of osteoporosis. ABSTRACT Dysregulated proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs ...
Jingmin Che +7 more
wiley +1 more source
Reduce oral health anesthetic emissions for the sake of health. [PDF]
Front Dent MedNevison M +4 more
europepmc +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao +3 more
wiley +1 more source
Review of the Effects of Anesthetic Techniques and Medications on the Immune Response During the Perioperative Period. [PDF]
Med Sci MonitRadkowski P +6 more
europepmc +1 more source
Progress On Sensorineural Hearing Loss: Mechanisms and Therapies
Sensory Neuroscience, EarlyView.ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang +9 more
wiley +1 more source
Towards Prescribing Pathways for Oral Health Practitioners in Australia: Addressing Barriers to Patient-Centered Care. [PDF]
J Public Health DentCarlson-Jones W +8 more
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Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring
Environmental Toxicology, EarlyView.ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário +8 more
wiley +1 more source
Comparison of total intravenous anesthesia and combined inhalation and intravenous anesthesia on survival after tumor surgery: a propensity score matched cohort study. [PDF]
Front Med (Lausanne)Wang Y +9 more
europepmc +1 more source