Results 231 to 240 of about 18,601 (330)

Effects of the Dietary Supplement 5α‐Hydroxy‐Laxogenin in the Orchiectomized Rat Model

Drug Testing and Analysis, EarlyView.
The dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated in the castrated male rat for potential androgenic and anabolic effects. Moreover, androgen receptor binding of 5α‐hydroxy‐laxogenin was modelled by in silico docking. While molecular modelling supports androgen receptor binding, we observed neither androgenic nor anabolic effects ...
Daniel Derwand, Oliver Zierau, Clemens Alexander Wolf, Gerhard Wolber, Annekathrin Martina Keiler   +4 more
wiley   +1 more source

Molecular Properties of the "Ideal" Inhaled Anesthetic

, 1995
Jerry M. Gonzales
openalex   +1 more source

The Common Inhalation Anesthetic Isoflurane Induces Apoptosis and Increases Amyloid β Protein Levels [PDF]

, 2006
Zhongcong Xie, Yuanlin Dong, Uta Maeda, Paul H. Alfillé, Deborah J. Culley, Gregory Crosby, Rudolph E. Tanzi   +6 more
openalex   +1 more source

Calpain inhibition in a transgenic model of calpastatin overexpression facilitates reversal of myocardial hypertrophy

ESC Heart Failure, Volume 12, Issue 3, Page 2256-2266, June 2025.
Abstract Aims It was recently demonstrated that the intracellular signalling phosphatase calcineurin is subject to cleavage by the protease calpain, resulting in a truncated calcineurin fragment that is a strong inductor of myocardial hypertrophy. We now address the question of whether inhibition of calpain function in cardiomyocytes, and thereby ...
Gregor Sachse, Johanna Tennigkeit, Nikolaos Pagonas, Philipp Hillmeister, Ivo Buschmann, Martin Czolbe, Peter Nordbeck, Joachim Schmitt, Daniel Patschan, Oliver Ritter   +9 more
wiley   +1 more source

Effects of sevoflurane and isoflurane on acute myocardial infarction model establishment in mice. [PDF]

Biochem Biophys Rep
Li JN, Zeng LH, Jin L, Liu JT.
europepmc   +1 more source

Identification of serum C4BPA as a potential diagnostic marker of right ventricular remodelling via proteomic analysis

ESC Heart Failure, EarlyView.
Abstract Aims Right ventricular (RV) remodelling, a progressive condition characterized by maladaptive cardiac structural and functional changes, primarily results from prolonged pressure overload in patients with pulmonary hypertension (PH). Accurate, universal and easy‐to‐use biomarkers for assessing the severity of RV remodelling are lacking.
Xuenan Wang, Cheng Yu, Meiling Li, Huiling Cai, Yongjian Yang, Cong Lan   +5 more
wiley   +1 more source

The SiBI™ Connector: A New Medical Device to Facilitate Preoxygenation and Reduce Waste Anesthetic Gases During Inhaled Induction with Sevoflurane

, 2000
Marie-José Colas, Jean-Pierre Tétrault, Lynne Dumais, Patrick B. Truong, Yves Claprood, René Martin   +5 more
openalex   +1 more source

Anesthetics change the oral microbial composition of children and increase the abundance of the genus Haemophilus. [PDF]

Transl Pediatr
Xie D, Zhang N, Hu Y, Li Q, Yang Y, Zou Y, Lu Y, Hu W, Guo L, Li H.   +9 more
europepmc   +1 more source

Acetylcholine Receptors Do Not Mediate the Immobilization Produced by Inhaled Anesthetics

, 2002
Edmond I. Eger, Yi Zhang, Michael J. Laster, Pamela Flood, Joan J. Kendig, James M. Sonner   +5 more
openalex   +1 more source

Combined medetomidine, midazolam, and butorphanol anesthesia in mice has a central stress-relieving effect similar to that of isoflurane anesthesia. [PDF]

J Vet Med Sci
Yokosuka M, Osaka M, Tohei A.
europepmc   +1 more source