Results 231 to 240 of about 358,345 (314)

Deciphering the Heterogeneity of Pulmonary Macrophages in Response to Fine Particles

Small, EarlyView.
This study introduces a dual‐labeled gold nanoparticle model to capture particle–responsive cells via integrating fluorescence‐activated cell sorting and single‐cell RNA sequencing. Fourteen macrophage subsets are identified with response and function heterogeneity, among which AMs_3, AMs_7, and recMacs_4 subsets show stronger phagocytic activation ...
Qing'e Shan, Zheng Dong, Ning Li, Zijie Zhou, Jiayu Ren, Wei Liu, Feng Xu, Yu Qi, Juan Ma, Yi Liu, Shuping Zhang, Sijin Liu   +11 more
wiley   +1 more source

Using pupillary pain index to assess the analgesic effect of interscalene block in arthroscopic rotator cuff repair under sevoflurane anesthesia: A prospective observational study. [PDF]

Medicine (Baltimore)
Lu YH, Huang LY, Pan RY, Chen SY, Chen YC, Yeh CC.   +5 more
europepmc   +1 more source

Hydrogel Microneedle Array‐Based Transdermal Dressing System for Multiplexed Assessment and Intelligent Therapy of Chronic Wounds

Small, EarlyView.
This work develops a theranostic wound microneedle dressing integrates a therapeutic MXene‐infused hydrogel with a high‐conductive sensor array enabled by a novel laser‐scribing technique. The platform actively promotes wound healing and provides antibacterial action while continuously monitoring seven key biomarkers.
Md Sharifuzzaman, Gauri Hasabnis, Sheikh Ahmed Abu Saleh, Leonard Siebert, Jan‐Bernd Hövener, Gregor Maschkowitz, Zeynep Altintas   +6 more
wiley   +1 more source

Propofol TIVA vs. inhalational anesthesia for spine surgery: in‑hospital mortality and postoperative complications in a nationwide Korean cohort. [PDF]

BMC Anesthesiol
Oh TK, Kim S, Song IA.
europepmc   +1 more source

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

Small, EarlyView.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad, Shunping Han, Rifka Utami, Rafal Baker, Dina Helal, Zhuoni Li, Mark Tricklebank, Yannis Paloyelis, Julie Wang, Marija M. Petrinovic, Sukhi Bansal, Khuloud T. Al‐Jamal   +11 more
wiley   +1 more source

Impact of opioid-free anesthesia on the overall benefit of analgesia score after laparoscopic cholecystectomy: protocol and statistical analysis plan for a multicenter, randomized, controlled trial. [PDF]

Ann Med
Zhao HX, Han L, Wang D, Jin J, Ji FH, Guo W, Liu H, Sudhan N, Li Y, Peng K.   +9 more
europepmc   +1 more source

Targeted Nanocomplex Delivery for Protecting Vascular Integrity and Enhancing Anticancer Effects in Hepatocellular Carcinoma

Small Science, EarlyView.
Herein, a liver‐targeted nanohybrid formulation, SGLC/DOX@AG, is developed to enhance doxorubicin delivery and reduce vascular toxicity in hepatocellular carcinoma (HCC) treatment. Incorporating an albumin–glucosamine lipid complex, the system shows potent anticancer effects and minimized side effects across in vitro, in vivo, and cancer‐on‐a‐chip ...
Hyelim Kim, Han Sol Lee, June Hong Ahn, Tae‐Wan Kwon, So‐Yeol Yoo, Donghyuk Seo, Sang Kyum Kim, Hee Ho Park, Seung‐Woo Cho, Wonhwa Lee, Jae‐Young Lee, Hong Nam Kim   +11 more
wiley   +1 more source

Preventive strategies for reducing intraoperative awareness due to errors in anesthetic drug delivery systems: a narrative review. [PDF]

Front Pharmacol
Chen Q, Peng S, Luo W, Li S, Zhang Z.
europepmc   +1 more source

Comparing isoflurane and desflurane: A prospective randomised blinded clinical trial in horses undergoing elective surgery

Veterinary Record, EarlyView.
Abstract Background The recovery period is associated with the greatest risk of injury for horses undergoing anaesthesia. Recovery quality and duration can be influenced by the volatile agent. Methods This prospective, randomised blinded clinical investigation recruited 101 healthy client‐owned horses undergoing elective surgery at one UK equine ...
Kate White, John Hird, Polly Taylor
wiley   +1 more source

Comparison of the anesthetic efficacy and recovery quality of remimazolam besylate versus sevoflurane for pediatric circumcision: a single-center, prospective, assessor-blinded, randomized controlled study protocol. [PDF]

BMC Anesthesiol
Zhang Y, Guo S, Wang L, Zeng Q, Cui H, Mo Y.   +5 more
europepmc   +1 more source