Results 211 to 220 of about 44,337 (260)

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, Volume 31, Issue 6, Page 561-577, June 2026.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Resultant greenhouse gases from the use of inhaled corticosteroid based on Global Initiative for Asthma (GINA) guidelines: a primary care used case from Singapore. [PDF]

NPJ Prim Care Respir Med
Ng DX, Leow MQH, Koh YLE, Aau WK, Tan NC.   +4 more
europepmc   +1 more source

Opposing Association of Lung Neutrophils and PD‐L1+ Monocytes in Age‐Related Severity of SARS‐CoV‐2 Infection

Aging Cell, Volume 25, Issue 6, June 2026.
Aging skews pulmonary myeloid responses during acute SARS‐CoV‐2 infection toward severe disease. Disease progression is characterized by excessive lung neutrophil accumulation together with impaired activation of classical monocytes, including a defect in PD‐L1 upregulation.
Serban Morosan, Clémence Granier, Noëlline Guillou, Selma Bennacer, Eléonore Weber‐Delacroix, Julianne Peronnet, François Lanthiez, Sandrine Barthelemy, Christelle Enond, Jean‐Luc Diehl, Elena Paillaud, Carine El‐Sissy, Anne‐Geneviève Marcelin, Vincent Calvez, Stéphane Marot, Amélie Guihot, Christophe Parizot, Karim Dorgham, Guy Gorochov, Christophe Combadière, Alexandre Boissonnas   +20 more
wiley   +1 more source

Are single-nucleotide polymorphisms previously linked to inhaled corticosteroid response associated with obese-asthma in children? [PDF]

Pediatr Allergy Immunol
Longo C, Chiv R, Xu Z, Forno E, Chen W, Boeck A, Granell R, Salvermoser M, Schaub B, Celedón JC, Turner S, Vijverberg S, Maitland-van der Zee AH.   +12 more
europepmc   +1 more source

Five‐Grass‐Pollen Sublingual Immunotherapy Drops Are Efficacious and Well Tolerated in Adults: The RHAPSODY Phase III Trial

Allergy, Volume 81, Issue 6, Page 2123-2132, June 2026.
The RHAPSODY multinational study investigated 26 months of continuous treatment with 5‐grass‐pollen sublingual SLIT drops in adults with moderate‐to‐severe grass‐pollen‐induced allergic rhinoconjunctivitis. The primary efficacy endpoint (the average daily total combined score) showed statistically significant differences in favour of the active ...
Alain Didier, Ruta Gronskyte Juhl, Terrie Dalgaard, Antoine Chartier, Philippe Devillier   +4 more
wiley   +1 more source

Effectiveness of indacaterol/glycopyrronium/mometasone for refractory asthmatic cough after switching from inhaled corticosteroid/long-acting β₂-agonist therapy. [PDF]

J Allergy Clin Immunol Glob
Niimi A, Ohbayashi H, Asamoto H, Kamei T, Kiyosue A, Fukushima Y, Matsuoka H, Miyao N, Tochigi T, Yamagata E, Tsuji T, Mikami T, Saito J, Kanemitsu Y, Tajiri T, Hara J.   +15 more
europepmc   +1 more source

Early Risk Assessment and Recognition of Allergies in Children: Rationale, Methodology, and Proposed Algorithms

Allergy, Volume 81, Issue 6, Page 1971-1984, June 2026.
ABSTRACT Background Atopic diseases—including atopic dermatitis (AD), food allergy (FA), allergic rhinitis (AR), and asthma—are the most common chronic conditions in childhood and adolescence, affecting up to 30% of the global population. In Germany alone, more than 2.1 million children and adolescents are affected.
E. Hamelmann, B. Schaub, K. Beyer, K. Blümchen, M. Gerstlauer, M. V. Kopp, L. Lange, S. Lau, N. Maison, H. Ott, S. M. Schmidt, T. Spindler, C. Traidl‐Hoffmann, C. Vogelberg   +13 more
wiley   +1 more source

Inhaled corticosteroid delivery is markedly affected by breathing pattern and valved holding chamber model. [PDF]

Pediatr Pulmonol
Ojanperä L, Lehtimäki L, Huhtala H, Csonka P.   +3 more
europepmc   +1 more source

Characterizing and assessing vision‐related quality of life among patients discontinued treatment for neovascular age‐related macular degeneration

Acta Ophthalmologica, Volume 104, Issue 4, Page e406-e415, June 2026.
Abstract Purpose This study characterized and assessed vision‐related quality of life (VRQoL) in patients with neovascular age‐related macular degeneration (nAMD) who discontinued treatment with intravitreal anti‐vascular endothelial growth factor (anti‐VEGF), comparing them to those undergoing treatment.
Noreddin Shekho, Anna Stage Vergmann, Frederik Nørregaard Pedersen, Lonny Stokholm, Benjamin Sommer Thinggaard   +4 more
wiley   +1 more source

Dupilumab Plus Medium-Dose Inhaled Corticosteroid (ICS) Improves Outcomes Compared With Placebo Plus Continued High-Dose ICS in Children With Uncontrolled Moderate-to-Severe Type 2 Asthma. [PDF]

Pediatr Pulmonol
Bacharier LB, Maspero JF, Papadopoulos NG, Gagnon R, Guilbert TW, Xia C, Ledanois O, Soliman M.   +7 more
europepmc   +1 more source