PSO exhibited protective effects against CSE‐induced pulmonary inflammation by reducing macrophage and eosinophil infiltration, preventing alveolar destruction, and enhancing antioxidant defense by lowering serum MDA levels in a murine COPD model. These findings support the potential role as a dietary supplement for the prevention or attenuation of ...
Gaewarin Liamvilairat +5 more
wiley +1 more source
Carbon emissions from the increasing use of inhaled corticosteroid-LABA medications: a primary care used case from Singapore. [PDF]
Tan NC +4 more
europepmc +1 more source
Obesity and New‐Onset Asthma Risk in Chronic Rhinosinusitis: A Population‐Based Cohort Study
This population‐based cohort study used the TriNetX U.S. Collaborative Network to evaluate the association between body mass index and subsequent asthma outcomes among adults with chronic rhinosinusitis. Elevated BMI was associated with a dose‐dependent increase in risk of new‐onset asthma and asthma exacerbations across 1‐, 2‐, and 5‐year follow‐up ...
Austin J. Lee +2 more
wiley +1 more source
Dose of Inhaled Corticosteroid in Chronic Obstructive Pulmonary Disease and Risks of Osteoporosis or Fracture-A Systematic Review and Meta-Analysis. [PDF]
Kwok WC +6 more
europepmc +1 more source
Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq +2 more
wiley +1 more source
Comparative Risk for Neuropsychiatric Events in Leukotriene Receptor Antagonist vs. Inhaled Corticosteroid in Children With Asthma: A Nationwide Observational Study With a Complementary Analysis Using Natural Language Processing. [PDF]
Kim S +13 more
europepmc +1 more source
Unraveling Oral Dysbiosis: Microbial Complexity in Common Oral Diseases
The oral microbiome undergoes dynamic establishment from birth, maturing into a resilient ecosystem. Perturbation of this homeostasis—driven by dietary, immunological, and anatomical factors—triggers dysbiosis, which underpins the pathogenesis of major oral diseases, including dental caries, periodontal disease, salivary gland disorders, oral mucosal ...
Zixi Kang +8 more
wiley +1 more source
Supratherapeutic Inhaled Corticosteroid Use in Patients Initiating on Biologic Therapies for Severe Asthma: A Nationwide Cohort Study. [PDF]
Hjortdahl F +14 more
europepmc +1 more source
Pretreatment with New Zealand blackcurrant anthocyanins nonsignificantly reduced TNF‐α–induced PAI‐1 release in bronchial epithelial cells. The small sample size may have influenced the lack of statistical significance. This study provides preliminary evidence of possible effects of NZBC anthocyanins on PAI‐1 secretion but warrants further extensive ...
Madiha Ajaz +5 more
wiley +1 more source
Outpatient inhaled corticosteroid use in bronchopulmonary dysplasia. [PDF]
Leon C +7 more
europepmc +1 more source

