Results 261 to 270 of about 48,911 (308)

Inhaled Corticosteroid Treatment for Asthma

Allergy and Asthma Proceedings, 1995
Increased numbers of goblet cells associated with decrease in the ciliated epithelium occur at an early stage in the patient with asthma. Recent bronchial biopsy studies have demonstrated that these changes may occur even in the mildest asthmatic patient.
L A, Laitinen, A, Laitinen
openaire   +2 more sources

Effects of inhaled corticosteroids on growth

Journal of Allergy and Clinical Immunology, 1998
Inhaled corticosteroids are an established treatment for asthma in childhood. The risk of adverse events associated with conventional doses of inhaled corticosteroids is low, but in children with asthma concern remains about the potential effects of these compounds on growth. Short-term growth in children can be measured with knemometry. This technique
openaire   +2 more sources

Developing the Ideal Inhaled Corticosteroid

Chest, 2006
Inhaled corticosteroids (ICS) are considered the most effective asthma therapy, but concerns remain about side effects. The ideal ICS would have a larger therapeutic ratio than currently available agents, allowing doses to be increased but without greatly increasing the frequency or severity of adverse events.
openaire   +2 more sources

Systemic effects of inhaled corticosteroids

Current Opinion in Pulmonary Medicine, 2012
Although inhaled corticosteroids (ICSs) are the mainstay of therapy in asthma, their use raises certain safety concerns. We review the articles appearing in the last year which have addressed the safety of ICSs when used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).Recent studies suggest that patients with asthma as ...
Pierre, Ernst, Samy, Suissa
openaire   +2 more sources

Inhaled corticosteroids—effect on bone?

Respiratory Medicine, 1993
Asthmatic patients receiving long-term therapy with oral prednisolone have been found to have an increased incidence of vertebral fractures. Measurements of bone density have shown that diminished bone density is associated with administration of oral corticosteroids rather than with the disease.
openaire   +2 more sources

Inhaled Corticosteroids in Children

Drug Safety, 1993
Inhaled corticosteroids are effective for the treatment of asthma. Because of the appreciation of the importance of airway inflammation in the pathogenesis of the disease, these drugs are being used more frequently not only in severe but also in moderate asthma.
BONER, Attilio, PIACENTINI, Giorgio
openaire   +3 more sources

An overview of the safety of inhaled corticosteroids

International Journal of Risk & Safety in Medicine, 1994
The papers contained in this issue of the journal deal comprehensively with specific areas in which the safety of inhaled corticosteroids might give cause for concern as a result of their effects on skeletal metabolism, childhood growth, the endocrine system and the skin.
M N, Dukes, S T, Holgate, R A, Pauwels
openaire   +2 more sources

Advances in inhaled corticosteroid pharmacology

Allergy and Asthma Proceedings, 2007
Inhaled corticosteroids have been the backbone of asthma therapy for the past 20 plus years. Although they have, for the most part, been effective in controlling asthma symptoms and preventing exacerbations, not all patients are universally responsive to their beneficial effects.
openaire   +2 more sources

[Inhaled corticosteroids for COPD].

Nederlands tijdschrift voor geneeskunde, 2003
Over 60% of patients with COPD are treated with inhaled corticosteroids (ICS), even though their use is still subject to debate. The inflammatory process in the lungs of patients with COPD is dominated by macrophages, CD8+ T-lymphocytes, neutrophilic granulocytes and mast cells, as well as an increased production and/or concentration of IL-8, TNF-alpha
openaire   +2 more sources

Safety of inhaled corticosteroids in children

Pediatric Pulmonology, 2002
AbstractInhaled corticosteroids (ICS) are now first‐line therapy for persistent asthma in children. The major safety concerns of long‐term ICS therapy for childhood asthma are potential effects on adrenal function, growth, and bone mass. Dosage, type of inhaler device, and individual drug characteristics influence systemic effects of ICS.
openaire   +2 more sources