Results 31 to 40 of about 3,797,701 (299)

Advances and prospects in coal dust control and explosion prevention technologies

open access: yesMeitan kexue jishu
As the dominant energy source in China, coal mining, storage, and transportation continually face prominent occupational health risks and coal dust explosion hazards, which severely constrain the industry’s safety and sustainable development.
Zhenmin LUO   +6 more
doaj   +1 more source

Optimization of reactivity temperature feedback and core design of GFR

open access: yesHe jishu
BackgroundGas-cooled fast reactor (GFR) is one of the six recommended nuclear reactor types of Generation IV Forum (GIF) with the lowest technical maturity.
ZHOU Mengfei, YI Xuan, LIU Guoming
doaj   +1 more source

Optimizing the Design of Small Fast Spectrum Battery-Type Nuclear Reactors

open access: yesEnergies, 2014
This study is focused on defining and optimizing the design parameters of inherently safe “battery” type sodium-cooled metallic-fueled nuclear reactor cores that operate on a single stationary fuel loading at full power for 30 years.
Staffan Qvist
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Inherent Safety Analysis and Sustainability Evaluation of Chitosan Production from Shrimp Exoskeleton in Colombia

open access: yesWater, 2020
Waste valorization strategies are key to achieve more sustainable production within the shrimp industry. The crustacean exoskeletons can be potentially used to obtain value-added products such as chitosan.
A. Zuorro   +2 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Evaluation of Shrimp Waste Valorization Combining Computer-Aided Simulation and Numerical Descriptive Inherent Safety Technique (NuDIST)

open access: yesApplied Sciences, 2020
Nowadays, inherently safer designs are considered as key priorities to prevent or mitigate serious incidents with devastating consequences. The need for process safety assessment during early design phases has motivated the development of several ...
A. Zuorro   +4 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Study on Inherent Safety Characteristic on Thermal-hydraulic of Pool-type Sodium-cooled Fast Reactors

open access: yesYuanzineng kexue jishu, 2023
The concept of the inherent safety characteristic on thermal-hydraulic of the pool-type sodium-cooled fast reactor was proposed and its formation mechanism was analyzed.
ZHOU Zhiwei;XUE Xiuli;YANG Yong;YANG Hongyi
doaj  

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