Results 41 to 50 of about 1,049,137 (382)
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Gifts and inheritances in Ireland. ESRI WP579, December 2017 [PDF]
Information on the frequency, value and composition of household wealth transfers has been fairly limited in Ireland and this paper aims to fill this gap by drawing on the detailed data now available on the pattern of gifts and inheritances from the 2013
Lawless, Martina, Lynch, Donal
core
IntroductionThis study explores the emotional impact of religion-related films through a “cinematherapy” lens. It aims to analyze the emotional patterns in a curated selection of religion-related films compared to a broader sample of acclaimed movies ...
Bai Xue +4 more
doaj +1 more source
To inherit heritage or to inherit inheritance?
The Republic of Serbia is one of the few, if not the only country in the world that, at ratification and translation of the term “baština”- heritage which appears in two significant and related international conventions of UNESCO, used different terms: “baština”- "heritage", with regard to the Convention Concerning the Protection of the World ...
openaire +4 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Lonicera microphylla Willd. ex Roem. & Schult. 1819 is a medicinal plant species, especially for treating chronic fever and dysentery. This study aimed to characterize the chloroplast genome of L.
Xiaomei Wei +5 more
doaj +1 more source
Epigenetic Inheritance: Concepts, Mechanisms and Perspectives
Parents’ stressful experiences can influence an offspring’s vulnerability to many pathological conditions, including psychopathologies, and their effects may even endure for several generations.
Irene Lacal, R. Ventura
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Gametic configuration and inheritance of SSR markers in tetraploid interspecific and intergeneric citrus somatic hybrids : S02P20 [PDF]
Citrus somatic hybridization has become an integral part of citrus improvement programs worldwide. More than 100 somatic hybrids have been created by Cirad.
Chahidi, B. +8 more
core
Unrelated Helpers in a Primitively Eusocial Wasp: Is Helping Tailored Towards Direct Fitness? [PDF]
The paper wasp Polistes dominulus is unique among the social insects in that nearly one-third of co-foundresses are completely unrelated to the dominant individual whose offspring they help to rear and yet reproductive skew is high.
AE Liebert +41 more
core +5 more sources

