Key role for inhibins in effective T cell activation, migration and Th17 differentiation [PDF]
FEBS Open BioOur group has previously reported that inhibin and its molecular pair, TGF‐β type III receptor (TβRIII), regulate T cell development within the thymus. In addition, inhibins play a key role in immune tolerance through the modulation of dendritic cell (DC)
Gloria Soldevila +1 more
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Inactivating the Uninhibited: The Tale of Activins and Inhibins in Pulmonary Arterial Hypertension. [PDF]
Int J Mol Sci, 2023 Advances in technology and biomedical knowledge have led to the effective diagnosis and treatment of an increasing number of rare diseases. Pulmonary arterial hypertension (PAH) is a rare disorder of the pulmonary vasculature that is associated with high
Ryanto GRT, Musthafa A, Hara T, Emoto N.
europepmc +2 more sources
A Key Role for Inhibins in Dendritic Cell Maturation and Function. [PDF]
PLoS ONE, 2016 Inhibins are members of the TGFβ superfamily, which regulate many cellular processes including differentiation, proliferation, survival and apoptosis. Although initially described as hormones regulating the hypothalamus-pituitary-gonadal axis, based on ...
Roxana Olguín-Alor +5 more
doaj +2 more sources
Inhibins Tune the Thymocyte Selection Process by Regulating Thymic Stromal Cell Differentiation
Journal of Immunology Research, 2015 Inhibins and Activins are members of the TGF-β superfamily that regulate the differentiation of several cell types. These ligands were initially identified as hormones that regulate the hypothalamus-pituitary-gonadal axis; however, increasing evidence ...
Ebzadrel Carbajal-Franco +4 more
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Evolving roles of activins and inhibins in ovarian cancer pathophysiology.
Am J Physiol Cell Physiol, 2023 Activins and Inhibins are unique members of the Transforming Growth Factor-b (TGFb) family of growth factors, with the ability to exert autocrine, endocrine, and paracrine effects in a wide range of complex physiologic and pathologic processes.
Evans ET, Horst B, Arend RC, Mythreye K.
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Activins and Inhibins in Cardiovascular Pathophysiology [PDF]
BiomoleculesActivins and inhibins, members of the transforming growth factor β (TGFβ) superfamily, were initially recognized for their opposing effects on the secretion of follicle-stimulating hormone.
Wenyi Tang +6 more
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Functional data analysis of FSH and inhibin B levels in four ovulatory cycles shows a changing oscillatory interaction during the follicular phase [PDF]
Frontiers in EndocrinologyObjectiveThe pituitary hormone FSH (follicle-stimulating hormone) and the follicular granulosa cell hormone inhibin B are important in follicle development ending in ovulation.
Stephen J. Usala +2 more
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The Role of TGF-β Signaling Pathway in Determining Small Ruminant Litter Size [PDF]
BiologyThe transforming growth factor-beta (TGF-β) superfamily plays a crucial role in regulating female reproductive traits, particularly litter size, in small ruminants, such as sheep and goats.
Ying Han +4 more
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Immunolocalization of activin and inhibin at different stages of follicular development in the lizard Sceloporus torquatus [PDF]
Heliyon, 2023 The activins and inhibins are glycoproteins with a role in the follicular development of vertebrates, that are found in follicular fluid and somatic follicular cells, with a different pattern among taxa.
N.B. Cruz-Cano +5 more
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Maternal TGF-β ligand Panda breaks the radial symmetry of the sea urchin embryo by antagonizing the Nodal type II receptor ACVRII. [PDF]
PLoS BiologyIn the highly regulative embryo of the sea urchin Paracentrotus lividus, establishment of the dorsal-ventral (D/V) axis critically depends on the zygotic expression of the TGF-β nodal in the ventral ectoderm.
Praveen Kumar Viswanathan +4 more
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