Results 41 to 50 of about 2,795 (215)

TGF-β: An Important Mediator of Allergic Disease and a Molecule with Dual Activity in Cancer Development

Journal of Immunology Research, 2014
The transforming growth factor-β (TGF-β) superfamily is a family of structurally related proteins that includes TGF-β, activins/inhibins, and bone morphogenic proteins (BMPs).
Belen Tirado-Rodriguez, Enrique Ortega, Patricia Segura-Medina, Sara Huerta-Yepez   +3 more
doaj   +1 more source

Prevalence of HCMV, HHV‐6, and HSV‐1/2 in the semen of men attending infertility clinics and their association with semen parameters

UroPrecision, EarlyView.
Abstract Background Viral infections have been identified as potential disruptors of male reproductive health. This study aimed to investigate the prevalence of human cytomegalovirus (HCMV), human herpesvirus 6 (HHV‐6), and herpes simplex virus types 1 and 2 (HSV‐1/2) DNA in semen samples from fertile and infertile men within the potential impact of ...
Seyedeh Zahra Hashemi, Neda Pirbonyeh, Fahime Edalat, Narges Eslami, Saeed Tajik, Arash Letafati, Jamal Sarvari, Afagh Moattari   +7 more
wiley   +1 more source

Activins and inhibins in mammalian testis development: New models, new insights

, 2012
The discovery of activin and inhibins as modulators of the hypothalamic-pituitary-gonadal axis has set the foundation for understanding their central importance to many facets of development and disease.
Mendis, S H, Loveland, K L, Itman, Catherine, Barakat, B   +3 more
core   +1 more source

Effects of Inhibin A on Apoptosis and Proliferation of Bovine Granulosa Cells

Animals, 2020
Inhibin A is well known for its inhibitory properties against follicle-stimulating hormone (FSH), released through a pituitary−gonadal negative feedback loop to regulate follicular development.
Huitao Xu, Adnan Khan, Shanjiang Zhao, Huan Wang, Huiying Zou, Yunwei Pang, Huabin Zhu   +6 more
doaj   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Inhibin βB Mediates Oligotrophic Adaptation via Regulating Muscle Satellite Cell Proliferation and Differentiation in Schizopygopsis younghusbandi

Integrative Zoology, EarlyView.
① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption. ② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.
Weiqiang Li, He Gao, Chaowei Zhou, Luo Lei, Junting Li, Chao Ma, Zitu Ma, Mengwei Yao, Kexin Ma, Yunpeng Xiang, Yan Zhou, Yongrui Lu, Da Ji, Minghong Wei, Luohao Xu, Zhaofang Han, Haiping Liu   +16 more
wiley   +1 more source

Cryopreservation of Spermatozoa Prior and Post‐Orchiectomy in Patients With Testicular Germ Cell Cancer—Does the Timing Matter?

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell cancer (TGCC) is the most frequent malignancy in young men of reproductive age. According to guidelines, semen cryopreservation should be performed prior to orchiectomy. Lack of time and local facilities as well as mental pressure are challenges in terms of fertility preservation before surgery.
Yuhe Tang, Gerald Pühse, Sabine Kliesch, Jann‐Frederik Cremers, Maria Schubert   +4 more
wiley   +1 more source

Population Briefs, Vol. 8, no. 1 [PDF]

, 2002
IN THIS ISSUE: Bridging the safe motherhood knowledge gap | Decelerating pace and human development crucial elements of fertility transition | Illuminating the role of inhibins and activins in fertility | Motivations for and barriers to study ...
Population Council
core   +1 more source

The levels of inhibin A and inhibin B in PCOS patients

GSC Biological and Pharmaceutical Sciences, 2023
Background: Polycystic ovary syndrome (PCOS) is one of the main factors leading to infertility and ovulatory dysfunction in women. The aim of the current research is to study the levels of Inhibin A and Inhibin B in women with PCOS, depending on the level of Anti-millerian hormone.
Gurbanova Jamila Fazil, Hasanova Afat Sadig, Maharramova Najiba Tofig, Islamova Jahan Ali   +3 more
openaire   +2 more sources

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source