Results 31 to 40 of about 2,795 (215)
Medicina, 2021 Granulosa cell tumor of the ovary (GCT) is a rare ovarian tumor with nonspecific symptoms. Studies reported that GCT are usually secreting estrogens and inhibins, especially inhibin B.
Corina Gică +6 more
doaj +1 more source
Influence of non-gonadotrophic hormones on gonadal function
, 2000 Inhibins and activins are dimeric glycoproteins, member of the transforming growth factor b (TGF b) superfamily. The main source and targets of inhibins during the fertile age, in non pregnant women, are the ovaries, while during pregnancy placental ...
DRIUL L. +7 more
core +2 more sources
Frontiers in Endocrinology, 2021 The number of mitochondria in the oocyte along with their functions (e.g., energy production, scavenger activity) decline with age progression. Such multifaceted functions support several processes during oocyte maturation, ranging from energy supply to ...
Marco Colella +11 more
doaj +1 more source
Physiological roles of activins in the human ovary
Journal of Bio-X Research, 2018 . Initially discovered in the pituitary as stimulators of follicle stimulating hormone, activins are homo- or heterodimers of inhibin subunits, which belong to the transforming growth factor-β superfamily.
Hsun-Ming Chang, Peter C.K. Leung
doaj +1 more source
Gene expression networks underlying ovarian development in wild largemouth bass (Micropterus salmoides). [PDF]
PLoS ONE, 2013 Oocyte maturation in fish involves numerous cell signaling cascades that are activated or inhibited during specific stages of oocyte development. The objectives of this study were to characterize molecular pathways and temporal gene expression patterns ...
Christopher J Martyniuk +7 more
doaj +1 more source
Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility
Journal of Applied Toxicology, EarlyView.ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues +3 more
wiley +1 more source
The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models
Journal of Skin Cancer, 2012 TGFβ1 is a member of a large growth factor family including activins/inhibins and bone morphogenic proteins (BMPs) that have a potent growth regulatory and immunomodulatory functions in normal skin homeostasis, regulation of epidermal stem cells ...
Adam B. Glick
doaj +1 more source
High concentrations of inhibin A and inhibin B in ovarian serous cystadenoma: Relationship with oestradiol and nitric oxide metabolites [PDF]
, 2000 Inhibin production has been demonstrated in malignant epithelial ovarian tumours, but secretion of inhibins by benign cystadenoma has not yet been reported.
BIFULCO, G. +14 more
core +1 more source
Hepatic Adenomas in Men: Diagnostic Considerations and Management in the Modern Era
Journal of Surgical Oncology, EarlyView.ABSTRACT Hepatic adenomas (HAs) are rare benign liver tumors traditionally associated with young women, yet contemporary epidemiologic trends reveal increasing recognition among men. Historically, universal resection in males has been recommended because of a nearly tenfold increased risk of malignant transformation as reported by Farges et al.
Teresa Belledent +9 more
wiley +1 more source
Pediatric Discovery, EarlyView.MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen +11 more
wiley +1 more source