Results 31 to 40 of about 13,977 (219)

Secondary Amenorrhea and Infertility Due to an Inhibin B Producing Granulosa Cell Tumor of the Ovary. A Rare Case Report and Literature Review

Medicina, 2021
Granulosa cell tumor of the ovary (GCT) is a rare ovarian tumor with nonspecific symptoms. Studies reported that GCT are usually secreting estrogens and inhibins, especially inhibin B.
Corina Gică, Ruxandra-Gabriela Cigăran, Radu Botezatu, Anca Maria Panaitescu, Brîndușa Cimpoca, Gheorghe Peltecu, Nicolae Gică   +6 more
doaj   +1 more source

Evidence of a local negative role for cocaine and amphetamine regulated transcript (CART), inhibins and low molecular weight insulin like growth factor binding proteins in regulation of granulosa cell estradiol production during follicular waves in cattle

Reproductive Biology and Endocrinology, 2006
The ability of ovarian follicles to produce large amounts of estradiol is a hallmark of follicle health status. Estradiol producing capacity is lost in ovarian follicles before morphological signs of atresia.
Ireland James J, Jimenez-Krassel Fermin, Kobayashi Yasuhiro, Smith George W   +3 more
doaj   +1 more source

Ovarian Aging: Role of Pituitary-Ovarian Axis Hormones and ncRNAs in Regulating Ovarian Mitochondrial Activity

Frontiers in Endocrinology, 2021
The number of mitochondria in the oocyte along with their functions (e.g., energy production, scavenger activity) decline with age progression. Such multifaceted functions support several processes during oocyte maturation, ranging from energy supply to ...
Marco Colella, Marco Colella, Marco Colella, Danila Cuomo, Teresa Peluso, Ilaria Falanga, Massimo Mallardo, Mario De Felice, Mario De Felice, Concetta Ambrosino, Concetta Ambrosino, Concetta Ambrosino   +11 more
doaj   +1 more source

Gene expression networks underlying ovarian development in wild largemouth bass (Micropterus salmoides). [PDF]

PLoS ONE, 2013
Oocyte maturation in fish involves numerous cell signaling cascades that are activated or inhibited during specific stages of oocyte development. The objectives of this study were to characterize molecular pathways and temporal gene expression patterns ...
Christopher J Martyniuk, Melinda S Prucha, Nicholas J Doperalski, Philipp Antczak, Kevin J Kroll, Francesco Falciani, David S Barber, Nancy D Denslow   +7 more
doaj   +1 more source

Physiological roles of activins in the human ovary

Journal of Bio-X Research, 2018
. Initially discovered in the pituitary as stimulators of follicle stimulating hormone, activins are homo- or heterodimers of inhibin subunits, which belong to the transforming growth factor-β superfamily.
Hsun-Ming Chang, Peter C.K. Leung
doaj   +1 more source

The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models

Journal of Skin Cancer, 2012
TGFβ1 is a member of a large growth factor family including activins/inhibins and bone morphogenic proteins (BMPs) that have a potent growth regulatory and immunomodulatory functions in normal skin homeostasis, regulation of epidermal stem cells ...
Adam B. Glick
doaj   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland, Amber Nakar Weinstein, Eric C. Kao, Xiaonan Zhao, Monika Weisz‐Hubshman   +4 more
wiley   +1 more source

Bone turnover across the menopause transition The role of gonadal inhibins

Annals of the New York Academy of Sciences, 2010
Accumulating evidence demonstrates increasing bone turnover and bone loss in women prior to menopause and decreases in serum estradiol levels. Increased follicle‐stimulating hormone levels have been correlated with some of these peri‐menopausal changes ...
Kristy M. Nicks, Tristan W. Fowler, Nisreen S Akel, D. Perrien, L. Suva, D. Gaddy   +5 more
semanticscholar   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

Animal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad, Hubdar Ali Kolachi, Jesse Oluwaseun Ayantoye, Xiaomeng Zhang, Muhammad Usman Mehmood, Rajilan Hilali Shanga, Pengcheng Wan, Xueming Zhao   +7 more
wiley   +1 more source