Results 21 to 30 of about 4,666 (217)

Efficacy of cyclin-dependent kinase 4/6 inhibitors in combination with hormonal therapy in patients with recurrent granulosa cell tumor of the ovary: A case series

Gynecologic Oncology Reports, 2023
Cyclin-dependent kinase inhibitors are approved in combination with hormonal therapy for treatment of hormone receptor expressing breast cancers. Activity in hormone receptor expressing gynecologic cancers has been postulated. Granulosa cell tumor of the
Benjamin B. Albright, Stephanie Shuey, Angeles Alvarez Secord, Laura J. Havrilesky, Andrew Berchuck, Rebecca A. Previs   +5 more
doaj   +1 more source

Cancer Treatment and Bone Health [PDF]

, 2018
Considerable advances in oncology over recent decades have led to improved survival, while raising concerns about long-term consequences of anticancer treatments.
A Falahati-Nini, A Garg, A Lipton, A Llombart, A Morishima, A Tomkinson, AM Brufsky, AR Hong, B Buehring, BF Boyce, BL Clarke, BL Clarke, C Christensen, C Magno, C Poznak Van, C Shapiro, C Wilson, Catherine Handforth, CH Kasperk, CJ Stava, D Goldray, D Vanderschueren, DA Cameron, DA Galvão, DL Hershman, DM Huber, DS Perrien, Early Breast Cancer Trialists, EP Smith, F Mazzuca, FA Trémollieres, GK Ellis, HG Bone, HW Daniell, I Fogelman, I Sestak, J Morote, J Pfeilschifter, J Planas, Janet Brown, JD Wilson, JE Lester, JE Lester, JF Forbes, JL Mohler, JM Bruder, KB Emerton, KM Nicks, L Bošković, L Vehmanen, LC Hofbauer, LC Hofbauer, LH Klotz, LP Fried, M Bauer, M Datta, M Gnant, M Gnant, M Kalder, M Kalder, M Rabaglio, MD Michaelson, MG Oefelein, MM Agarwal, MR Smith, MR Smith, MR Smith, MR Smith, MR Smith, MR Smith, N Majithia, N Napoli, ND James, ND Wagner-Johnston, P Hadji, P Hadji, P Hadji, P Hadji, P Rodrigues, PD Miller, PE Goss, PE Goss, PL Nguyen, R Choo, R Coleman, R Coleman, R Eastell, R Eastell, R Soleimani, RA Adler, RE Coleman, RJ Segal, Robert Coleman, S Dhesy-Thind, S D’Oronzo, SL Greenspan, Stella D’Oronzo, SY Ying, T Kameda, T Liu, T Rana, T Saarto, TA Guise, TH Diamond, TJ Powles, V Carnevale, V Subbiah, VB Shahinian, W Vale, WJ Boyle   +109 more
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Primary retroperitoneal extraovarian granulosa cell tumor

Autopsy and Case Reports, 2022
Extraovarian granulosa cell tumors (GCTs) develop from ectopic gonadal tissue situated along the embryonal route of the genital ridge. Primary retroperitoneal tumors are extremely rare, with an incidence of 02% -06% and 80-85% probability of malignancy.
Pragya Sharma, Vikram Singh, Niharika Mishra, Manoj Gopinath, Prashant Gupta   +4 more
doaj  

Pituitary-testicular axis dysfunction in methimazole-induced hypothyroidism in rats

Journal of Veterinary Research, 2019
Introduction: Thyroid hormones play a major role in the regulation of testicular maturation and growth and in the control of Sertoli and Leydig cell functions in adulthood.
Gołyński Marcin, Metyk Michał, Szkodziak Piotr, Lutnicki Krzysztof, Kalisz Grzegorz, Szczepanik Marcin, Wilkołek Piotr, Dobrowolski Piotr   +7 more
doaj   +1 more source

Aplicações das dosagens de inibinas em Ginecologia e Obstetrícia Clinical usefulness of inhibin assays in Gynecology and Obstetrics

Revista Brasileira de Ginecologia e Obstetrícia, 2009
Na mulher, a principal fonte de inibina B são as células da granulosa de folículos em crescimento, enquanto a inibina A é secretada principalmente pelo corpo lúteo e pela placenta.
Fernando Marcos dos Reis, Carolina Passos de Rezende   +1 more
doaj   +1 more source

Differential expression of follistatin and FLRG in human breast proliferative disorders [PDF]

, 2009
Background Activins are growth factors acting on cell growth and differentiation. Activins are expressed in high grade breast tumors and they display an antiproliferative effect inducing G0/G1 cell cycle arrest in breast cancer cell lines.
Enrrico Bloise, Henrique L Couto, Lauretta Massai, Pasquapina Ciarmela, Marzia Mencarelli, Lavinia E Borges, Michela Muscettola, Giovanni Grasso, Vania F Amaral, Geovanni D Cassali, Felice Petraglia, Fernando M Reis, GP Risbridger, C Di Loreto, FM Reis, JS Jeruss, QY Liu, JE Burdette, JE Burdette, SJ Lin, Y Komatsu, CA Harrison, O Hashimoto, A Schneyer, C Glister, SJ Lee, JJ Hill, YG Chen, D Razanajaona, A Deli, H Ogino, J Krneta, P Ciarmela, PB Torres, MC Ferreira, V Maguer-Satta, P Florio, SC Klein, L Massai, FM Reis, C Courtillot, UA Bussmann, DL Page, S Saito, B Refaat, K Ogawa, C Welt, Y Kang, J Massagué   +48 more
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Cloning of a novel inhibin alpha cDNA from rhesus monkey testis

Reproductive Biology and Endocrinology, 2004
Background Inhibins are dimeric gonadal protein hormones that negatively regulate pituitary FSH synthesis and secretion. Inhibin B is produced by testicular Sertoli cells and is the primary circulating form of inhibin in most adult male mammals.
Woodruff Teresa K, Bernard Daniel J, Plant Tony M   +2 more
doaj   +1 more source

Activin A Modulates Betaglycan Shedding via the ALK4-SMAD3-Dependent Pathway in Endometriotic Cells

Biomolecules, 2022
The TGF-β superfamily members, activins and inhibins, are mainly involved in cell proliferation, cell survival, invasion, immune surveillance, and lesion growth in endometriosis.
Agnes N. Mwaura, Muhammad A. Riaz, Jane B. Maoga, Ezekiel Mecha, Charles O. A. Omwandho, Georgios Scheiner-Bobis, Ivo Meinhold-Heerlein, Lutz Konrad   +7 more
doaj   +1 more source

Anti-Mullerian hormone attenuates the effects of FSH on follicle development in the mouse ovary [PDF]

, 2001
Although ovarian follicle growth is under the influence of many growth factors and hormones of which FSH remains one of the most prominent regulators.
Durlinger, A.L.L. (Alexandra), Grootegoed, J.A. (Anton), Gruijters, M.J.G. (Maria), Jong, F.H. (Frank) de, Karels, B. (Bas), Kramer, P., Kumar, T.R. (Rajendra), Matzuk, M.M., Rose, U.M., Themmen, A.P.N. (Axel), Uilenbroek, J.Th.J. (Jan)   +10 more
core   +3 more sources

Reproductive hormones in breast cancer bone metastasis: The role of inhibins

Journal of Bone Oncology, 2016
The spread of breast cancer cells to bone and survival in this new metastatic environment is influenced not only by the genetic signature of the cells, but also multiple host cells and soluble factors produced locally (paracrine) or from distant sites ...
Caroline Wilson
doaj   +1 more source