Results 21 to 30 of about 2,795 (215)
Gynecologic Oncology Reports, 2023 Cyclin-dependent kinase inhibitors are approved in combination with hormonal therapy for treatment of hormone receptor expressing breast cancers. Activity in hormone receptor expressing gynecologic cancers has been postulated. Granulosa cell tumor of the
Benjamin B. Albright +5 more
doaj +1 more source
Primary retroperitoneal extraovarian granulosa cell tumor
Autopsy and Case Reports, 2022 Extraovarian granulosa cell tumors (GCTs) develop from ectopic gonadal tissue situated along the embryonal route of the genital ridge. Primary retroperitoneal tumors are extremely rare, with an incidence of 02% -06% and 80-85% probability of malignancy.
Pragya Sharma +4 more
doaj
Pituitary-testicular axis dysfunction in methimazole-induced hypothyroidism in rats
Journal of Veterinary Research, 2019 Introduction: Thyroid hormones play a major role in the regulation of testicular maturation and growth and in the control of Sertoli and Leydig cell functions in adulthood.
Gołyński Marcin +7 more
doaj +1 more source
Revista Brasileira de Ginecologia e Obstetrícia, 2009 Na mulher, a principal fonte de inibina B são as células da granulosa de folículos em crescimento, enquanto a inibina A é secretada principalmente pelo corpo lúteo e pela placenta.
Fernando Marcos dos Reis +1 more
doaj +1 more source
Cloning of a novel inhibin alpha cDNA from rhesus monkey testis
Reproductive Biology and Endocrinology, 2004 Background Inhibins are dimeric gonadal protein hormones that negatively regulate pituitary FSH synthesis and secretion. Inhibin B is produced by testicular Sertoli cells and is the primary circulating form of inhibin in most adult male mammals.
Woodruff Teresa K +2 more
doaj +1 more source
Reproductive hormones in breast cancer bone metastasis: The role of inhibins
Journal of Bone Oncology, 2016 The spread of breast cancer cells to bone and survival in this new metastatic environment is influenced not only by the genetic signature of the cells, but also multiple host cells and soluble factors produced locally (paracrine) or from distant sites ...
Caroline Wilson
doaj +1 more source
Activin A Modulates Betaglycan Shedding via the ALK4-SMAD3-Dependent Pathway in Endometriotic Cells
Biomolecules, 2022 The TGF-β superfamily members, activins and inhibins, are mainly involved in cell proliferation, cell survival, invasion, immune surveillance, and lesion growth in endometriosis.
Agnes N. Mwaura +7 more
doaj +1 more source
Inhibins: paracrine and endocrine effects in female reproductive function
, 1999 A great deal of new information has arisen in the past 2 years concerning the physiology of inhibins and their clinical relevance in reproductive medicine.
FALETTI, A. +4 more
core +1 more source
Mechanisms and Impact of Hypoxia Regulated Inhibins in Cancer [PDF]
, 2022 Inhibins are heterodimeric ligands within the TGFβ superfamily, comprised of an α-subunit (INHA) and a β-subunit (either INHBA or INHBB) with emergent roles in cancer.
Horst, Ben Allen
core +1 more source
Intra-ovarian roles of activins and inhibins
, 2012 Granulosa cells are the main ovarian source of inhibins, activins and activin-binding protein (follistatin) while germ (oogonia, oocytes) and somatic (theca, granulosa, luteal) cells express activin receptors, signaling components and inhibin co-receptor
Phil G. Knight +5 more
core +1 more source