Results 41 to 50 of about 4,682 (173)

Recognizing menopause in women with amenorrhea induced by cytotoxic chemotherapy for endocrine-responsive early breast cancer. [PDF]

open access: yes, 2012
Cytotoxic anticancer treatment may induce amenorrhea or menopause to a variable extent. These side effects may not only impair or impede fertility but also cause sexual dysfunction, bone loss, and menopausal symptoms, with a strikingly negative effect on
Appetecchia, M   +5 more
core   +1 more source

The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models

open access: yesJournal of Skin Cancer, 2012
TGFβ1 is a member of a large growth factor family including activins/inhibins and bone morphogenic proteins (BMPs) that have a potent growth regulatory and immunomodulatory functions in normal skin homeostasis, regulation of epidermal stem cells ...
Adam B. Glick
doaj   +1 more source

Physiological roles of activins in the human ovary

open access: yesJournal of Bio-X Research, 2018
. Initially discovered in the pituitary as stimulators of follicle stimulating hormone, activins are homo- or heterodimers of inhibin subunits, which belong to the transforming growth factor-β superfamily.
Hsun-Ming Chang, Peter C.K. Leung
doaj   +1 more source

Update on male reproductive endocrinology. [PDF]

open access: yes, 2018
Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
core   +1 more source

Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat [PDF]

open access: yes, 2017
Case summary A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE).
Fowkes, R C   +8 more
core   +2 more sources

TGF-β: An Important Mediator of Allergic Disease and a Molecule with Dual Activity in Cancer Development

open access: yesJournal of Immunology Research, 2014
The transforming growth factor-β (TGF-β) superfamily is a family of structurally related proteins that includes TGF-β, activins/inhibins, and bone morphogenic proteins (BMPs).
Belen Tirado-Rodriguez   +3 more
doaj   +1 more source

Effects of Inhibin A on Apoptosis and Proliferation of Bovine Granulosa Cells

open access: yesAnimals, 2020
Inhibin A is well known for its inhibitory properties against follicle-stimulating hormone (FSH), released through a pituitary−gonadal negative feedback loop to regulate follicular development.
Huitao Xu   +6 more
doaj   +1 more source

Premature ovarian failure

open access: yesOrphanet Journal of Rare Diseases, 2006
Premature ovarian failure (POF) is a primary ovarian defect characterized by absent menarche (primary amenorrhea) or premature depletion of ovarian follicles before the age of 40 years (secondary amenorrhea).
Persani Luca, Beck-Peccoz Paolo
doaj   +1 more source

The pituitary TGFb1 system as a novel target for the treatment of resistant prolactinomas [PDF]

open access: yes, 2016
Prolactinomas are the most frequently observed pituitary adenomas and most of themrespond well to conventional treatment with dopamine agonists (DAs).
Camilletti, María Andrea   +3 more
core   +2 more sources

Clinical correlation between premature ovarian failure and a chromosomal anomaly in a 22-year-old Caucasian woman: a case report

open access: yesJournal of Medical Case Reports, 2012
Introduction Premature ovarian failure is defined as the cessation of ovarian activity before the age of 40 years. It is biochemically characterized by low levels of gonadal hormones (estrogens and inhibins) and high levels of gonadotropins (luteinizing ...
Dell’Edera Domenico   +10 more
doaj   +1 more source

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