Results 11 to 20 of about 6,274,440 (386)
Inhibiting the Inhibition: A Neuronal Network for Sound Localization in Reverberant Environments [PDF]
The precedence effect describes the phenomenon whereby echoes are spatially fused to the location of an initial sound by selectively suppressing the directional information of lagging sounds (echo suppression). Echo suppression is a prerequisite for faithful sound localization in natural environments but can break down depending on the behavioral ...
Pecka, Michael+8 more
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AbstractTraditional lasers function using resonant cavities, in which the round-trip optical path is equal to an integer multiple of the intracavity wavelengths to constructively enhance the spontaneous emission rate. Taking advantage of the cavity enhancement effect, the narrowest sub-10-mHz-linewidth laser and a 10−16-fractional-frequency-stability ...
Tiantian Shi, Duo Pan, Jingbiao Chen
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Sequential presentation protects working memory from catastrophic interference [PDF]
Neural network models of memory are notorious for catastrophic interference: old items are forgotten as new items are memorized (e.g., French, 1999; McCloskey & Cohen, 1989).
Cowan N., Gliksman Y., McCloskey M.
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Plasticity of Inhibition [PDF]
Until recently, the study of plasticity of neural circuits focused almost exclusively on potentiation and depression at excitatory synapses on principal cells. Other elements in the neural circuitry, such as inhibitory synapses on principal cells and the synapses recruiting interneurons, were assumed to be relatively inflexible, as befits a role of ...
DimitriýM. Kullmann+3 more
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Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and "mood" (as a fine-tuning device), respectively, of network oscillations.
Freund, Tamás F., Katona, István
openaire +2 more sources
Angiotensin-neprilysin inhibition versus enalapril in heart failure.
BACKGROUND We compared the angiotensin receptor-neprilysin inhibitor LCZ696 with enalapril in patients who had heart failure with a reduced ejection fraction. In previous studies, enalapril improved survival in such patients.
J. McMurray+10 more
semanticscholar +1 more source
Background Monoamine oxidase has been implicated in numerous neurological disorders. Although synthetic monoamine oxidase inhibitors (MAOI) have emerged with many side effects, the aspiration of natural based MAOI has greatly increased.
Priyanka Dhiman+2 more
doaj +1 more source
Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome [PDF]
Hutchinson–Gilford progeria syndrome (HGPS) is a genetic disorder characterized by premature aging features. Cells from HGPS patients express progerin, a truncated form of Lamin A, which perturbs cellular homeostasis leading to nuclear shape alterations,
Aguado J.+12 more
core +1 more source
Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile [PDF]
Factor XIIIa (FXIIIa) is a transglutaminase that catalyzes the last step in the coagulation process. Orthostery is the only approach that has been exploited to design FXIIIa inhibitors.
Afosa, Daniel K.+4 more
core +7 more sources