Results 11 to 20 of about 4,778,507 (336)
AbstractTraditional lasers function using resonant cavities, in which the round-trip optical path is equal to an integer multiple of the intracavity wavelengths to constructively enhance the spontaneous emission rate. Taking advantage of the cavity enhancement effect, the narrowest sub-10-mHz-linewidth laser and a 10−16-fractional-frequency-stability ...
Tiantian Shi, Duo Pan, Jingbiao Chen
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Plasticity of Inhibition [PDF]
Until recently, the study of plasticity of neural circuits focused almost exclusively on potentiation and depression at excitatory synapses on principal cells. Other elements in the neural circuitry, such as inhibitory synapses on principal cells and the synapses recruiting interneurons, were assumed to be relatively inflexible, as befits a role of ...
DimitriýM. Kullmann+3 more
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Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and "mood" (as a fine-tuning device), respectively, of network oscillations.
Freund, Tamás F., Katona, István
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Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes. [PDF]
Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block ...
Doudna, Jennifer A+5 more
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G-6-P synthase enzyme has been involved in the synthesis of the microbial cell wall, and its inhibition may lead to the antimicrobial effect. In the present study, we designed a library of amygdalin derivatives, and two most active derivatives selected ...
Amit Lather+2 more
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Functional mechanisms involved in the internal inhibition of taboo words [PDF]
The present study used functional magnetic resonance imaging to investigate brain processes associated with the inhibition of socially undesirable speech.
Brass, Marcel+3 more
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Background Plants have always played important role in treating human and animal diseases as a therapeutic agent for traditional medicine. Through extensive research throughout the world, potential of natural products have been identified to control the ...
Ritu Kataria, Anurag Khatkar
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In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors
Background Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme which catalyses xanthine to uric acid which is found to be associated with ...
Neelam Malik+2 more
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