Results 11 to 20 of about 4,254,417 (298)

In Vitro Inhibition Effects of 2-Amino Thiazole Derivatives on Lactoperoxidase Enzyme Activity

open access: yesCumhuriyet Science Journal, 2022
Lactoperoxidase (LPO E.C. 1.11.1.7) is a member of the peroxidase family and is an important glycoprotein containing heme group in its structure and showing the antimicrobial effect on disease causing microorganisms in the digestive system of newborn ...
Işıl Nihan Korkmaz
doaj   +1 more source

Molecular docking, synthesis, kinetics study, structure–activity relationship and ADMET analysis of morin analogous as Helicobacter pylori urease inhibitors

open access: yesBMC Chemistry, 2019
Background Urease are responsible for several pathogenic states in human as well as in animals and its inhibition is utmost urgent. Clinically used drugs are associated with many side effects; recently several researches have shown that flavonoids have ...
Ritu Kataria, Anurag Khatkar
doaj   +1 more source

Selective inhibition of BET bromodomains

open access: yesNature, 2010
Epigenetic proteins are intently pursued targets in ligand discovery. So far, successful efforts have been limited to chromatin modifying enzymes, or so-called epigenetic ‘writers’ and ‘erasers’.
P. Filippakopoulos   +24 more
semanticscholar   +1 more source

In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

open access: yesBMC Chemistry, 2019
Background Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome.
Neelam Malik   +2 more
doaj   +1 more source

Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND The angiotensin receptor-neprilysin inhibitor sacubitril-valsartan led to a reduced risk of hospitalization for heart failure or death from cardiovascular causes among patients with heart failure and reduced ejection fraction.
S. Solomon   +33 more
semanticscholar   +1 more source

Synthesis and antifungal activity of copper nanoparticles against Fusarium oxysporum pathogen of plants

open access: yesMaterials Research Express, 2023
For many decades, Cu ^2+ ions have been used as fungicides in agriculture. However, the accumulation of Cu ^2+ ions in the soil ecosystem will be disadvantage for environment.
Hanh Thi Truong   +2 more
doaj   +1 more source

Inhibitive effect of azine and diazine derivatives on the corrosion of 316L SS in acidic media

open access: yesZaštita Materijala, 2014
The inhibiting effect of some azine and diazine derivatives on the corrosion of cyclic stressed 316L SS specimens in 3 M HCl in the presence of organic derivatives with concentrations (1×10-6 M - 11×10-6 M) at 30oC was studied using weight loss and ...
A.S. Fouda, Desoky A.M. El, A.A. Keshk
doaj   +1 more source

Combined effect of heavy metals on the activated sludge process; pp. 305–314 [PDF]

open access: yesProceedings of the Estonian Academy of Sciences, 2018
Migration of heavy metals in the environment is a serious problem for wastewater treatment plants (WWTP) and the environment as a whole. The combined effect of eight heavy metals on the biological wastewater treatment process was analysed in this ...
Erki Lember   +3 more
doaj   +1 more source

The Detection of Potential Native Probiotics Lactobacillus spp. against Salmonella Enteritidis, Salmonella Infantis and Salmonella Kentucky ST198 of Lebanese Chicken Origin

open access: yesAntibiotics, 2022
Salmonella continues to be a major threat to public health, especially with respect to strains from a poultry origin. In recent years, an increasing trend of antimicrobial resistance (AMR) in Salmonella spp. was observed due to the misuse of antibiotics.
Rima El Hage   +9 more
doaj   +1 more source

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

open access: yesGenes & Development, 2007
The Hippo pathway plays a key role in organ size control by regulating cell proliferation and apoptosis in Drosophila. Although recent genetic studies have shown that the Hippo pathway is regulated by the NF2 and Fat tumor suppressors, the physiological ...
Bin Zhao   +15 more
semanticscholar   +1 more source

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