Results 11 to 20 of about 6,364,217 (385)
Communications Physics, 2021 AbstractTraditional lasers function using resonant cavities, in which the round-trip optical path is equal to an integer multiple of the intracavity wavelengths to constructively enhance the spontaneous emission rate. Taking advantage of the cavity enhancement effect, the narrowest sub-10-mHz-linewidth laser and a 10−16-fractional-frequency-stability ...
Tiantian Shi, Duo Pan, Jingbiao Chen
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Plasticity of Inhibition [PDF]
Neuron, 2012 Until recently, the study of plasticity of neural circuits focused almost exclusively on potentiation and depression at excitatory synapses on principal cells. Other elements in the neural circuitry, such as inhibitory synapses on principal cells and the synapses recruiting interneurons, were assumed to be relatively inflexible, as befits a role of ...
DimitriýM. Kullmann +3 more
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Sequential presentation protects working memory from catastrophic interference [PDF]
, 2020 Neural network models of memory are notorious for catastrophic interference: old items are forgotten as new items are memorized (e.g., French, 1999; McCloskey & Cohen, 1989).
Cowan N., Gliksman Y., McCloskey M.
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Neuron, 2007 Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and "mood" (as a fine-tuning device), respectively, of network oscillations.
Freund, Tamás F., Katona, István
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Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile [PDF]
, 2016 Factor XIIIa (FXIIIa) is a transglutaminase that catalyzes the last step in the coagulation process. Orthostery is the only approach that has been exploited to design FXIIIa inhibitors.
Afosa, Daniel K. +4 more
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Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes. [PDF]
, 2020 Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block ...
Doudna, Jennifer A +5 more
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Angiotensin-neprilysin inhibition versus enalapril in heart failure.
New England Journal of Medicine, 2014 BACKGROUND We compared the angiotensin receptor-neprilysin inhibitor LCZ696 with enalapril in patients who had heart failure with a reduced ejection fraction. In previous studies, enalapril improved survival in such patients.
J. McMurray +10 more
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Chemistry Central Journal, 2018 Background Monoamine oxidase has been implicated in numerous neurological disorders. Although synthetic monoamine oxidase inhibitors (MAOI) have emerged with many side effects, the aspiration of natural based MAOI has greatly increased.
Priyanka Dhiman +2 more
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Frontiers in Pediatrics, 2022 ObjectiveIn the current study, a person-centered approach was adopted to investigate the relationship between nutritional status and physical fitness profiles and executive functions (EF) in preadolescents.MethodsParticipants (Mage = 10.8 years; Male ...
Yuxin Zhu +4 more
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PARP inhibition: a promising therapeutic target in ovarian cancer [PDF]
, 2015 Ovarian cancer is burdened by the highest mortality rate among gynecological cancers. Gold standard is represented by the association of platinum-taxane -based chemotherapy and radical surgery.
Abdul Halim, T +14 more
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