Results 31 to 40 of about 6,398,774 (357)
BMC Chemistry, 2019 Background Urease are responsible for several pathogenic states in human as well as in animals and its inhibition is utmost urgent. Clinically used drugs are associated with many side effects; recently several researches have shown that flavonoids have ...
Ritu Kataria, Anurag Khatkar
doaj +1 more source
Functional mechanisms involved in the internal inhibition of taboo words [PDF]
, 2011 The present study used functional magnetic resonance imaging to investigate brain processes associated with the inhibition of socially undesirable speech.
Brass, Marcel +3 more
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Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors [PDF]
, 2013 Six new azo dyes containing of 5(4H)-oxazolone ring were prepared by diazotization of 4-aminohippuric acid and coupling with N,N-dimethylaniline, 1-naphthol and 2-naphthol and condensation with 4-fluoro benzaldehyde or 4-trifluoromethoxy benzaldehyde ...
Abbasalipour, V. +5 more
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Gain control with A-type potassium current: IA as a switch between divisive and subtractive inhibition [PDF]
, 2018 Neurons process information by transforming barrages of synaptic inputs into spiking activity. Synaptic inhibition suppresses the output firing activity of a neuron, and is commonly classified as having a subtractive or divisive effect on a neuron's ...
Goldwyn, Joshua H +3 more
core +5 more sources
In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors
BMC Chemistry, 2019 Background Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome.
Neelam Malik +2 more
doaj +1 more source
Selective inhibition of BET bromodomains
Nature, 2010 Epigenetic proteins are intently pursued targets in ligand discovery. So far, successful efforts have been limited to chromatin modifying enzymes, or so-called epigenetic ‘writers’ and ‘erasers’.
P. Filippakopoulos +24 more
semanticscholar +1 more source
Tetracycline Actions Relevant to Rosacea Treatment [PDF]
, 2009 Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
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Push-Pull Control of Motor Output [PDF]
, 2012 Inhibition usually decreases input–output excitability of neurons. If, however, inhibition is coupled to excitation in a push–pull fashion, where inhibition decreases as excitation increases, neuron excitability can be increased. Although the presence of
Heckman, C J +3 more
core +2 more sources
Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.
New England Journal of Medicine, 2019 BACKGROUND The angiotensin receptor-neprilysin inhibitor sacubitril-valsartan led to a reduced risk of hospitalization for heart failure or death from cardiovascular causes among patients with heart failure and reduced ejection fraction.
S. Solomon +33 more
semanticscholar +1 more source
The temporal dynamic of response inhibition in early childhood: An ERP study of partial and successful inhibition [PDF]
, 2014 Event-related potentials were recorded while five-year-old children completed a Go/No-Go task that distinguished between partial inhibition (i.e., response is initiated but cancelled before completion) and successful inhibition (i.e., response is ...
Dunn L. M. +4 more
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