Results 201 to 210 of about 4,254,417 (298)

A comprehensive investigation of expired dextromethorphan HBr drug as a carbon steel corrosion inhibitor using gravimetric, electrochemical, and theoretical computational approaches. [PDF]

Sci Rep
Khafagy ES, Lila ASA, Ashmawy AM, Deyab MA.   +3 more
europepmc   +1 more source

Exploring the anticancer potential of Tinospora cordifolia with computational insights into EGFR inhibition [PDF]

G. Asha, S. Lekshmi, K.P. Najmathunnisa, T. Rajva, Krishnakumar Velayudhannair, K.P. Safna Hussan   +5 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Research progress on protein tyrosine phosphatase A from Mycobacterium tuberculosis. [PDF]

Front Immunol
Cai Y, Zhang L.
europepmc   +1 more source

ACLY Inhibition In CKD

, 2023
O'Neil, Kian
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Fluoride toxicity and mitigation strategies in acidophilic bioleaching microorganisms. [PDF]

Appl Microbiol Biotechnol
Fritze MT, Hedrich S.
europepmc   +1 more source

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Nature Medicine, 2019
Kirsten L. Bryant, Clint A. Stalnecker, Daniel Zeitouni, Jennifer E. Klomp, S. Peng, A. Tikunov, V. Gunda, M. Pierobon, Andrew M. Waters, Samuel D. George, Garima Tomar, Bjoern Papke, G. A. Hobbs, Liang Yan, T. Hayes, J. Diehl, G. Goode, Nina V. Chaika, Yingxue Wang, Guo-Fang Zhang, A. Witkiewicz, E. Knudsen, E. Petricoin, P. Singh, J. Macdonald, N. Tran, C. Lyssiotis, H. Ying, Alec C. Kimmelman, A. Cox, C. Der   +30 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source