Results 231 to 240 of about 6,274,440 (386)

Targeting S-Nitrosylation to Overcome Therapeutic Resistance in NRAS-Driven Melanoma. [PDF]

Cancers (Basel)
Srivastava J, Premi S.
europepmc   +1 more source

THE MECHANISM OF THE INHIBITION BY CARBONIC ACID OF THE SMOOTH MUSCLE CONTRACTION PRODUCED BY HISTAMINE AND OXYTOCIN [PDF]

, 1959
B Halpern, R Binaghi, Matthias P. Mayer, C. Bugnard   +3 more
openalex   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

TAK1 inhibition activates pore-forming proteins to block intracellular bacterial growth through modulating mitochondria. [PDF]

Cell Death Dis
López-Pérez W, González-Calderón RE, Sai K, Rai P, MacStudy JM, Sakamachi Y, Parsons C, Kathariou S, Fessler MB, Ninomiya-Tsuji J.   +9 more
europepmc   +1 more source

Kinetics of the Thermal Decomposition of Dimethylmercury. I. Cyclopentane Inhibition [PDF]

, 1959
M. E. Russell, Richard B. Bernstein
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

Science, 2009
K. Olive, Michael A. Jacobetz, Christian J. Davidson, A. Gopinathan, D. McIntyre, D. Honess, B. Madhu, M. Goldgraben, Meredith E. Caldwell, D. Allard, K. Frese, G. DeNicola, C. Feig, C. Combs, Stephen P. Winter, Heather Ireland-Zecchini, S. Reichelt, W. Howat, A.-L. Chang, M. Dhara, Lifu Wang, F. Rückert, R. Grützmann, C. Pilarsky, K. Izeradjene, S. Hingorani, Pearl S Huang, S. Davies, W. Plunkett, M. Egorin, R. Hruban, Nigel Whitebread, Karen McGovern, J. Adams, C. Iacobuzio-Donahue, J. Griffiths, D. Tuveson   +36 more
semanticscholar   +1 more source

Hierarchical Organization of Bilateral Prefrontal-Basal Ganglia Circuits for Response Inhibition Control. [PDF]

Hum Brain Mapp
Lin L, Chen Y, Fan Z, Xiong W, Wang X, Ji H, Li J, Zhuang J.   +7 more
europepmc   +1 more source

THE INHIBITION OF MITOCHONDRIAL RESPIRATION BY 1,10-PHENANTHROLINE AND 2,2'-BIPYRIDINE AND THE POSSIBLE RELATIONSHIP TO OXIDATIVE PHOSPHORYLATION

, 1958
William C. Yang, Davi Yanasugondha, J. Webb   +2 more
openalex   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source