Results 281 to 290 of about 6,274,440 (386)

Patient-derived organoids reveal marked heterogeneity in chemosensitivity profiles of colorectal cancer and a potential association with HER2 status. [PDF]

Front Pharmacol
Liu J, Li D, Li J, Fu W, Jia Q, Bai Y, Huang A, Chen F.   +7 more
europepmc   +1 more source

The Inhibition of Perspiration by Means of the Topical Application of Malonic Acid Salts1

, 1957
Adolph Rostenberg, Elsa L. Gonzalez
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.

Cell Metabolism, 2016
Vicky Lampropoulou, A. Sergushichev, M. Bambouskova, S. Nair, E. Vincent, Ekaterina Loginicheva, L. Cervantes-Barragan, Xiucui Ma, S. C. Huang, Takla Griss, C. Weinheimer, S. Khader, G. Randolph, E. Pearce, Russell G. Jones, A. Diwan, M. Diamond, M. Artyomov   +17 more
semanticscholar   +1 more source

The influence of emotional stimuli on response inhibition: a systematic review in non-clinical adults. [PDF]

Front Psychol
Rincón-Pérez I, Sánchez-Carmona AJ, Levy D, López-Martín S, Hinojosa JA, Albert J.   +5 more
europepmc   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Activity guided discovery of dual inhibitors of α-glucosidase and β-glucuronidase from the leaves of <i>Millettia pachycarpa</i> Benth. [PDF]

J Enzyme Inhib Med Chem
He Y, Xu H, Tan S, Long J, Lei H, Xiao L, Qi X, Deng M, Xiong X, You J, Zhu L, Lü M, Liang S.   +12 more
europepmc   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Inhibition of Aminotripeptidase.

Experimental Biology and Medicine, 1952
Morris Ziff, Alfred A. Smith
openaire   +3 more sources