Results 21 to 30 of about 6,274,440 (386)
Scientific Reports, 2020 G-6-P synthase enzyme has been involved in the synthesis of the microbial cell wall, and its inhibition may lead to the antimicrobial effect. In the present study, we designed a library of amygdalin derivatives, and two most active derivatives selected ...
Amit Lather +2 more
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Frontiers in Molecular Neuroscience, 2022 GABAA receptors are ligand-gated ion channels, which are predominantly permeable for chloride. The neuronal K-Cl cotransporter KCC2 lowers the intraneuronal chloride concentration and thus plays an important role for GABA signaling. KCC2 loss-of-function
Tanja Herrmann +6 more
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PARP inhibition: a promising therapeutic target in ovarian cancer [PDF]
, 2015 Ovarian cancer is burdened by the highest mortality rate among gynecological cancers. Gold standard is represented by the association of platinum-taxane -based chemotherapy and radical surgery.
Abdul Halim, T +14 more
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BMC Chemistry, 2019 Background Plants have always played important role in treating human and animal diseases as a therapeutic agent for traditional medicine. Through extensive research throughout the world, potential of natural products have been identified to control the ...
Ritu Kataria, Anurag Khatkar
doaj +1 more source
Neural correlates of intentional and stimulus-driven inhibition: a comparison [PDF]
, 2014 People can inhibit an action because of an instruction by an external stimulus, or because of their own internal decision. The similarities and differences between these two forms of inhibition are not well understood. Therefore, in the present study the
Brass, Marcel +5 more
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BMC Chemistry, 2019 Background Urease are responsible for several pathogenic states in human as well as in animals and its inhibition is utmost urgent. Clinically used drugs are associated with many side effects; recently several researches have shown that flavonoids have ...
Ritu Kataria, Anurag Khatkar
doaj +1 more source
Study of Modern Control Methodologies Applied to Tumor Growth under Angiogenic Inhibition [PDF]
, 2014 Cancer treatment is one of the most important research fields of modern medicine. In the last decades, targeted molecular therapies showed pr osperous results. These treatments achieve tumor regression with limited side-effects. Mathem atical models
Angiogenic Inhibition +5 more
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In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors
BMC Chemistry, 2019 Background Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme which catalyses xanthine to uric acid which is found to be associated with ...
Neelam Malik +2 more
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Nitric oxide synthases: structure, function and inhibition.
Biochemical Journal, 2001 This review concentrates on advances in nitric oxide synthase (NOS) structure, function and inhibition made in the last seven years, during which time substantial advances have been made in our understanding of this enzyme family.
W. Alderton +2 more
semanticscholar +1 more source
Event-related brain potentials in the study of inhibition: cognitive control, source localization and age-related modulations [PDF]
, 2014 In the previous 15 years, a variety of experimental paradigms and methods have been employed to study inhibition. In the current review, we analyze studies that have used the high temporal resolution of the event-related potential (ERP) technique to ...
Guerrini, Chiara +6 more
core +2 more sources