Results 21 to 30 of about 6,364,217 (385)
Scientific Reports, 2020 G-6-P synthase enzyme has been involved in the synthesis of the microbial cell wall, and its inhibition may lead to the antimicrobial effect. In the present study, we designed a library of amygdalin derivatives, and two most active derivatives selected ...
Amit Lather +2 more
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Biomolecules, 2021 The type III secretion system (T3SS) is a virulence apparatus used by many Gram-negative pathogenic bacteria to cause infections. Pathogens utilizing a T3SS are responsible for millions of infections yearly. Since many T3SS knockout strains are incapable
Julia A. Hotinger +2 more
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Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]
, 2008 Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A. +3 more
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International Journal of Molecular Sciences, 2023 Cancer metastasis is a common biological phenomenon observed in malignant tumors that can lead to death in affected individuals [...]
Masa-Aki Shibata, Kohei Taniguchi
openaire +2 more sources
BMC Chemistry, 2019 Background Plants have always played important role in treating human and animal diseases as a therapeutic agent for traditional medicine. Through extensive research throughout the world, potential of natural products have been identified to control the ...
Ritu Kataria, Anurag Khatkar
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Toxins, 2021 Aflatoxin B1 (AFB1) is a potent carcinogenic mycotoxin that contaminates numerous crops pre- and post-harvest. To protect foods and feeds from such toxins without resorting to pesticides, the use of plant extracts has been increasingly studied.
Christopher Hernandez +6 more
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Functional mechanisms involved in the internal inhibition of taboo words [PDF]
, 2011 The present study used functional magnetic resonance imaging to investigate brain processes associated with the inhibition of socially undesirable speech.
Brass, Marcel +3 more
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In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors
BMC Chemistry, 2019 Background Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme which catalyses xanthine to uric acid which is found to be associated with ...
Neelam Malik +2 more
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Computational View toward the Inhibition of SARS-CoV-2 Spike Glycoprotein and the 3CL Protease
Computation, 2020 Since the outbreak of the 2019 novel coronavirus disease (COVID-19), the medical research community is vigorously seeking a treatment to control the infection and save the lives of severely infected patients. The main potential candidates for the control
Zhen Qiao +3 more
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Plants, 2022 Currently, there are no specific therapeutics for flavivirus infections, including dengue virus (DENV) and Zika virus (ZIKV). In this study, we evaluated extracts from the plants Hedyotis diffusa (HD) and Artemisia capillaris (AC) to determine the ...
Zhan Qiu Mao +2 more
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