Results 31 to 40 of about 6,364,217 (385)

Inhibition [PDF]

The Pedagogical Seminary, 1898
n ...
openaire   +1 more source

Molecular docking, synthesis, kinetics study, structure–activity relationship and ADMET analysis of morin analogous as Helicobacter pylori urease inhibitors

BMC Chemistry, 2019
Background Urease are responsible for several pathogenic states in human as well as in animals and its inhibition is utmost urgent. Clinically used drugs are associated with many side effects; recently several researches have shown that flavonoids have ...
Ritu Kataria, Anurag Khatkar
doaj   +1 more source

Anaerobic Co-Digestion of Tannery and Slaughterhouse Wastewater for Solids Reduction and Resource Recovery: Effect of Sulfate Concentration and Inoculum to Substrate Ratio

Energies, 2021
Anaerobic digestion is considered unsuitable for the bioremediation of tannery effluent due to process inhibition, mainly due to high concentrations of sulfur species, and the accumulation of H2S and/or NH3.
Ashton B. Mpofu, Victoria A. Kibangou, Walusungu M. Kaira, Oluwaseun O. Oyekola, Pamela J. Welz   +4 more
doaj   +1 more source

Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors [PDF]

, 2013
Six new azo dyes containing of 5(4H)-oxazolone ring were prepared by diazotization of 4-aminohippuric acid and coupling with N,N-dimethylaniline, 1-naphthol and 2-naphthol and condensation with 4-fluoro benzaldehyde or 4-trifluoromethoxy benzaldehyde ...
Abbasalipour, V., Fozooni, S., Hamidian, H., Namjou, M., Tagizadeh, R., Taheri, A.   +5 more
core   +1 more source

Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription. [PDF]

, 2020
Deregulated expression of MYC induces a dependence on the NUAK1 kinase, but the molecular mechanisms underlying this dependence have not been fully clarified.
Ade, C.P., Baluapuri, A., Chang, Y.C., Cossa, G., Eilers, M., Girard, C., Kempa, S., Kumar, A., Kuster, B., Lührmann, R., Mastrobuoni, G., Mumberg, D., Prinz, F., Roeschert, I., Schülein-Völk, C., Silveira Vidal, R., Walz, S., Wolf, E., Wortmann, L.   +18 more
core   +1 more source

Effect of Hyacinth Treatment by Hydrogen Peroxide Stabilized with Silver and Some Fungicides on the Fungal Infection of Substrate and Bulbs and on Plant Growth and Development

Agronomy, 2022
The aim of the study was to demonstrate the feasibility of using hydrogen peroxide stabilized with silver (H2O2-Ag+) and selected fungicides for the treatment of hyacinth bulbs and to determine their effects on the development of fungi colonizing the ...
Adam T. Wojdyła, Jacek S. Nowak, Jan Bocianowski, Jacek Wiśniewski, Emilia Waszkiewicz   +4 more
doaj   +1 more source

Selective inhibition of BET bromodomains

Nature, 2010
Epigenetic proteins are intently pursued targets in ligand discovery. So far, successful efforts have been limited to chromatin modifying enzymes, or so-called epigenetic ‘writers’ and ‘erasers’.
P. Filippakopoulos, J. Qi, S. Picaud, Yao Shen, William B. Smith, O. Fedorov, Elizabeth M. Morse, T. Keates, T. Hickman, I. Felletár, M. Philpott, S. Munro, M. Mckeown, Yuchuan Wang, A. Christie, N. West, M. J. Cameron, Brian E. Schwartz, T. Heightman, N. L. La Thangue, C. French, O. Wiest, A. Kung, S. Knapp, J. Bradner   +24 more
semanticscholar   +1 more source

Tetracycline Actions Relevant to Rosacea Treatment [PDF]

, 2009
Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
core   +1 more source

In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

BMC Chemistry, 2019
Background Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome.
Neelam Malik, Priyanka Dhiman, Anurag Khatkar   +2 more
doaj   +1 more source

Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.

New England Journal of Medicine, 2019
BACKGROUND The angiotensin receptor-neprilysin inhibitor sacubitril-valsartan led to a reduced risk of hospitalization for heart failure or death from cardiovascular causes among patients with heart failure and reduced ejection fraction.
S. Solomon, J. McMurray, I. Anand, J. Ge, C. Lam, A. Maggioni, F. Martinez, M. Packer, M. Pfeffer, B. Pieske, M. Redfield, J. Rouleau, D. V. van Veldhuisen, F. Zannad, M. Zile, Akshay S. Desai, Brian Claggett, P. Jhund, S. Boytsov, J. Comín-Colet, J. Cleland, H. Düngen, E. Goncalvesova, T. Katova, J. K. Kerr Saraiva, M. Lelonek, B. Merkely, M. Senni, Sanjiv J. Shah, Jingmin Zhou, A. Rizkala, J. Gong, V. Shi, M. Lefkowitz   +33 more
semanticscholar   +1 more source