Results 31 to 40 of about 6,274,440 (386)
Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection
Journal of Extracellular Vesicles, 2020 Zika virus (ZIKV) is mainly transmitted via mosquitos, but human-to-human transmissions also occur. The virus is shed into various body fluids including saliva, which represents a possible source of viral transmission.
Carina Conzelmann +8 more
doaj +1 more source
Selective inhibition of BET bromodomains
Nature, 2010 Epigenetic proteins are intently pursued targets in ligand discovery. So far, successful efforts have been limited to chromatin modifying enzymes, or so-called epigenetic ‘writers’ and ‘erasers’.
P. Filippakopoulos +24 more
semanticscholar +1 more source
Functional mechanisms involved in the internal inhibition of taboo words [PDF]
, 2011 The present study used functional magnetic resonance imaging to investigate brain processes associated with the inhibition of socially undesirable speech.
Brass, Marcel +3 more
core +1 more source
In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors
BMC Chemistry, 2019 Background Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome.
Neelam Malik +2 more
doaj +1 more source
Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.
New England Journal of Medicine, 2019 BACKGROUND The angiotensin receptor-neprilysin inhibitor sacubitril-valsartan led to a reduced risk of hospitalization for heart failure or death from cardiovascular causes among patients with heart failure and reduced ejection fraction.
S. Solomon +33 more
semanticscholar +1 more source
The temporal dynamic of response inhibition in early childhood: An ERP study of partial and successful inhibition [PDF]
, 2014 Event-related potentials were recorded while five-year-old children completed a Go/No-Go task that distinguished between partial inhibition (i.e., response is initiated but cancelled before completion) and successful inhibition (i.e., response is ...
Dunn L. M. +4 more
core +1 more source
Cognitive Control in Suicide Ideators and Suicide Attempters
Frontiers in Psychology, 2020 There is a need to understand more of the risk factors involved in the process from suicide ideation to suicide attempt. Cognitive control processes may be important factors in assessing vulnerability to suicide.
Silje Støle Brokke +5 more
doaj +1 more source
Flavonoids as inhibitors of human neutrophil elastase
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Elastase is a proteolytic enzyme belonging to the family of hydrolases produced by human neutrophils, monocytes, macrophages, and endothelial cells.
Katarzyna Jakimiuk +3 more
doaj +1 more source
Tumor Mutational Burden and Response Rate to PD-1 Inhibition.
New England Journal of Medicine, 2017 In a survey of the spectrum of mutational burdens in 27 types of cancers, there was a correlation between an increased mutational burden and the response to checkpoint inhibition of PD-1 and PD-L1.
M. Yarchoan +2 more
semanticscholar +1 more source