Results 31 to 40 of about 2,311,592 (246)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Kinetics of the Enzymatic Hydrolysis of Sweet Cassava Starch and Bitter Cassava Flour and Gadung (Dioscorea hispida Dennst) Flour at Low Temperature

Bulletin of Chemical Reaction Engineering & Catalysis, 2017
Starch is a potential substrate for this purpose, but the extra cost is needed to hydrolyze it into reducing sugar. As an alternative to the expensive and energy demanding conventional hydrolysis process, the low-temperature hydrolysis is being studied ...
Hargono Hargono, Bakti Jos, Andri Cahyo Kumoro   +2 more
doaj   +1 more source

Inhibition of DNA Methyltransferase Inhibits DNA Replication [PDF]

Journal of Biological Chemistry, 2000
Ectopic expression of DNA methyltransferase transforms vertebrate cells, and inhibition of DNA methyltransferase reverses the transformed phenotype by an unknown mechanism. We tested the hypothesis that the presence of an active DNA methyltransferase is required for DNA replication in human non-small cell lung carcinoma A549 cells.
J D, Knox, F D, Araujo, P, Bigey, A D, Slack, G B, Price, M, Zannis-Hadjopoulos, M, Szyf   +6 more
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Inhibitory Effects of Flavonoids from Citrus reticulata 'Chachi' Peel on the Formation of Advanced Glycation End-products

Shipin gongye ke-ji
This study investigated the inhibitory effects of extracts from Citrus reticulata 'Chachi' peels at different growth stages and the primary flavonoid components (nobiletin, hesperetin, and hesperidin) on fluorescent AGEs using the bovine serum albumin ...
Wanting WANG, Wanbing CHEN, Congyi ZHU, Mengxue YANG, Guohui ZHU, Jiwu ZENG   +5 more
doaj   +1 more source

Overcoming inhibitions [PDF]

Proceedings of the National Academy of Sciences, 2006
Organophosphorus nerve agents and pesticides (Fig. 1) markedly increase the amount and duration of the action of acetylcholine at all of the synaptic sites where it acts, resulting in overstimulation of critical processes that can lead to incapacitation, muscle paralysis, and death. In a recent issue of PNAS, Albuquerque et al. (1) reported that a drug
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Purification and Component Analysis of Total Flavonoids from Sea Buckthorn Peel Residue and Its Anti-Pancreatic Lipase

Shipin gongye ke-ji
In order to clarify the inhibition of total flavonoids purified extract (TFSE) of sea buckthorn peel residue on pancreatic lipase, this research optimized the purification condition of total flavonoids crude extract (TFCE) of sea buckthorn peel residue ...
Jiali SUN, Junfeng JIANG, Xiaojuan MOU, Zehui ZONG, Siyu YAN, JIALALIDING·Remuzha, Xiaowei BAO   +6 more
doaj   +1 more source

Morphological and Transcriptomic Analysis of the Inhibitory Effects of Lactobacillus plantarum on Aspergillus flavus Growth and Aflatoxin Production

Toxins, 2019
Lactobacillus plantarum, as a natural bio-preservative, has attracted a great deal of attention in recent years. In this study, 22 L. plantarum strains were tested against the aflatoxin-producing fungus, Aspergillus flavus; strain IAMU80070 showed the ...
Yueju Zhao, Chenxi Zhang, Yawa Minnie Elodie Folly, Jinghua Chang, Yan Wang, Lu Zhou, Heping Zhang, Yang Liu   +7 more
doaj   +1 more source