Results 31 to 40 of about 4,033,279 (373)
Tumor Mutational Burden and Response Rate to PD-1 Inhibition.
New England Journal of Medicine, 2017 In a survey of the spectrum of mutational burdens in 27 types of cancers, there was a correlation between an increased mutational burden and the response to checkpoint inhibition of PD-1 and PD-L1.
M. Yarchoan +2 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2023 Cancer metastasis is a common biological phenomenon observed in malignant tumors that can lead to death in affected individuals [...]
Masa-Aki Shibata, Kohei Taniguchi
openaire +2 more sources
Frontiers in Bioengineering and Biotechnology, 2022 Anaerobic ammonia oxidation (anammox) bacteria are inhibited by heavy metals at high concentrations but require trace amounts of some heavy-metal elements for growth and activity maintenance.
Kazuichi Isaka +6 more
doaj +1 more source
giMLPs: Gate with Inhibition Mechanism in MLPs [PDF]
arXiv, 2022 This paper presents a new model architecture, gate with inhibition MLP (giMLP).The gate with inhibition on CycleMLP (gi-CycleMLP) can produce equal performance on the ImageNet classification task, and it also improves the BERT, Roberta, and DeBERTaV3 models depending on two novel techniques.
arxiv
Inhibiting the Inhibition: A Neuronal Network for Sound Localization in Reverberant Environments [PDF]
The Journal of Neuroscience, 2007 The precedence effect describes the phenomenon whereby echoes are spatially fused to the location of an initial sound by selectively suppressing the directional information of lagging sounds (echo suppression). Echo suppression is a prerequisite for faithful sound localization in natural environments but can break down depending on the behavioral ...
Pecka, Michael +8 more
openaire +3 more sources
Inhibition of mutated, activated BRAF in metastatic melanoma.
New England Journal of Medicine, 2010 BACKGROUND The identification of somatic mutations in the gene encoding the serine-threonine protein kinase B-RAF (BRAF) in the majority of melanomas offers an opportunity to test oncogene-targeted therapy for this disease.
K. Flaherty +10 more
semanticscholar +1 more source
Temporarily Unavailable: Memory Inhibition in Cognitive and Computer Science [PDF]
Interacting with Computers, Volume 31, Issue 3, May 2019, pp.
231-249, 2019 Inhibition is one of the core concepts in Cognitive Psychology. The idea of inhibitory mechanisms actively weakening representations in the human mind has inspired a great number of studies in various research domains. In contrast, Computer Science only recently has begun to consider inhibition as a second basic processing quality beside activation ...
arxiv +1 more source
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.
New England Journal of Medicine, 2010 BACKGROUND Oncogenic fusion genes consisting of EML4 and anaplastic lymphoma kinase (ALK) are present in a subgroup of non-small-cell lung cancers, representing 2 to 7% of such tumors. We explored the therapeutic efficacy of inhibiting ALK in such tumors
E. Kwak +33 more
semanticscholar +1 more source
Firing regulation of fast-spiking interneurons by autaptic inhibition [PDF]
EPL 114 (2016) 30001, 2016 Fast-spiking (FS) interneurons in the brain are self-innervated by powerful inhibitory GABAergic autaptic connections. By computational modelling, we investigate how autaptic inhibition regulates the firing response of such interneurons. Our results indicate that autaptic inhibition both boosts the current threshold for action potential generation as ...
arxiv +1 more source