Results 61 to 70 of about 4,778,507 (336)
Coreceptors and Their Ligands in Epithelial γδ T Cell Biology
Frontiers in Immunology, 2018 Epithelial tissues line the body providing a protective barrier from the external environment. Maintenance of these epithelial barrier tissues critically relies on the presence of a functional resident T cell population.
Deborah A. Witherden +2 more
doaj +1 more source
Biochemical exploration of β-lactamase inhibitors
Frontiers in Genetics, 2023 The alarming rise of microbial resistance to antibiotics has severely limited the efficacy of current treatment options. The prevalence of β-lactamase enzymes is a significant contributor to the emergence of antibiotic resistance.
Varshaa Arer, Debasish Kar
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Functional diversity of supragranular GABAergic neurons in the barrel cortex
Frontiers in Neural Circuits, 2012 Although the neocortex forms a distributed system comprised of several functional areas, its vertical columnar organization is largely conserved across areas and species, suggesting the existence of a canonical neocortical microcircuit.
Luc J Gentet
doaj +1 more source
Interaural time difference processing in the mammalian medial superior olive [PDF]
, 2008 The dominant cue for localization of low-frequency sounds are microsecond differences in the time-of-arrival of sounds at the two ears [interaural time difference (ITD)].
Behrend, Oliver +3 more
core +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Selective attention and inhibition in young school-aged children [PDF]
Specijalna Edukacija i Rehabilitacija, 2019 The aims of this research were to determine the developmental dynamics of selective attention and inhibition in younger school-aged children, as well as its relationship with gender and intellectual abilities.
Gligorović Milica, Buha Nataša
doaj
Frontiers in Psychology, 2012 Previous research has shown that the intentional suppression of unwanted memories can lead to forgetting in later memory tests. However, the mechanisms underlying this effect remain unclear.
Gerd Thomas Waldhauser +2 more
doaj +1 more source
Impaired Competence for Pretense in Children with Autism: Exploring Potential Cognitive Predictors. [PDF]
, 2009 Lack of pretense in children with autism has been explained by a number of theoretical explanations, including impaired mentalising, impaired response inhibition, and weak central coherence.
AM Leslie +36 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source