Results 61 to 70 of about 6,274,440 (386)
Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats. [PDF]
, 2019 The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats.
Crawford, Elena +8 more
core +2 more sources
Frontiers in Psychology, 2020 Evidence suggests that executive and motor functions are functionally intertwined, with the interrelation between the two processes influenced by the developmental stage of the individual.
Christina Stuhr +3 more
doaj +1 more source
Shaping Functional Architecture by Oscillatory Alpha Activity: Gating by Inhibition
Frontiers in Human Neuroscience, 2010 In order to understand the working brain as a network, it is essential to identify the mechanisms by which information is gated between regions. We here propose that information is gated by inhibiting task-irrelevant regions, thus routing information to ...
O. Jensen, A. Mazaheri
semanticscholar +1 more source
KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors.
New England Journal of Medicine, 2020 BACKGROUND No therapies for targeting KRAS mutations in cancer have been approved. The KRAS p.G12C mutation occurs in 13% of non-small-cell lung cancers (NSCLCs) and in 1 to 3% of colorectal cancers and other cancers.
D. Hong +33 more
semanticscholar +1 more source
Bacteria Isolated from Ricinus communis and Its Possible Application in Agroecology
Journal of Pure and Applied Microbiology, 2019 Ricinus communis is a plant that is characterized by its different applications, in addition to being a wild plant favors its inclusion in agroecological practices because it does not represent high costs for producers.
Marisol Hernandez-Ramirez +4 more
doaj +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
The Modulatory Role of Cortisol in the Regulation of Sexual Behavior in Young Males
Frontiers in Behavioral Neuroscience, 2020 The proneness to be sexually aroused, to perform sexual acts, or to be sexually disinhibited during a particular mood varies across individuals. However, the physiological mechanisms underlying this specific and variable relationship between mood and sex-
Geraldine Rodríguez-Nieto +5 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
NMDAR inhibition-independent antidepressant actions of ketamine metabolites
Nature, 2016 Major depressive disorder affects around 16 per cent of the world population at some point in their lives. Despite the availability of numerous monoaminergic-based antidepressants, most patients require several weeks, if not months, to respond to these ...
P. Zanos +19 more
semanticscholar +1 more source
Current Directions in Psychological Science, 2022 Inhibition is considered an essential process to goal pursuit and as a result has become a central construct in many disciplines in psychology and adjacent fields. Despite a century’s worth of debate, however, there is little consensus about what inhibition actually is.
Kaitlyn M. Werner +2 more
openaire +3 more sources