Results 41 to 50 of about 6,774,149 (386)
Corrosion Inhibitors: Natural and Synthetic Organic Inhibitors
Lubricants, 2023 Corrosion is a major challenge in various industries and can cause significant damage to metal structures. Organic corrosion inhibitors are compounds that are used to reduce or prevent corrosion by forming a protective film on metal surfaces. The present
Ahmed A. Al-amiery +2 more
semanticscholar +1 more source
Monoamine Oxidase (MAO) as a Potential Target for Anticancer Drug Design and Development
Molecules, 2021 Monoamine oxidases (MAOs) are oxidative enzymes that catalyze the conversion of biogenic amines into their corresponding aldehydes and ketones through oxidative deamination.
Reem Aljanabi +5 more
doaj +1 more source
Cell Research, 2020 A new coronavirus SARS-CoV-2, also called novel coronavirus 2019 (2019-nCoV), started to circulate among humans around December 2019, and it is now widespread as a global pandemic.
Chunlong Ma +10 more
semanticscholar +1 more source
Фізика і хімія твердого тіла, 2020 Mechanical tests and studies of the structure of modified polyethylene film materials used as packaging elements of electronic devices have been carried out.
N. I. Domantsevich, B. P. Yatsushyn
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Biomedicines, 2021 The coronavirus disease 2019 (COVID-19) pandemic severely impacts health, economy, and society worldwide. Antiviral drugs against SARS-CoV-2 are urgently needed to cope with this global crisis. It has been found that the biogenesis and release mechanisms
Supasek Kongsomros +9 more
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Allosteric p97 inhibitors can overcome resistance to ATP-competitive p97 inhibitors for potential anti-cancer therapy [PDF]
, 2020 A major challenge of targeted cancer therapy is the selection for drug‐resistant mutations in tumor cells leading to loss of treatment effectiveness. p97/VCP is a central regulator of protein homeostasis and a promising anti‐cancer target because of its ...
Chou, Tsui-Fen +5 more
core +1 more source
Farnesyltransferase inhibitors
Seminars in Oncology, 2001 The targeting of molecular abnormalities in neoplasms may provide an opportunity to improve the selectivity of cancer therapy. Ras mutations are a common genetic event in human cancers. Other genetic changes in tumors can signal through ras-dependent pathways as well.
Hahn, S, Bernhard, E, Mckenna, W
openaire +3 more sources
Science Advances, 2019 Gingipains from Porphyromonas gingivalis drive Alzheimer’s pathology and can be blocked with small-molecule inhibitors. Porphyromonas gingivalis, the keystone pathogen in chronic periodontitis, was identified in the brain of Alzheimer’s disease patients.
S. Dominy +25 more
semanticscholar +1 more source
JAMA cardiology, 2020 This meta-analysis uses data from patients with type 2 diabetes from 6 outcomes trials to investigate the association of sodium-glucose cotransporter 2 inhibitors with cardiovascular- and kidney disease–related outcomes.
D. McGuire +13 more
semanticscholar +1 more source
Identification of a New Ribonucleoside Inhibitor of Ebola Virus Replication
Viruses, 2015 The current outbreak of Ebola virus (EBOV) in West Africa has claimed the lives of more than 15,000 people and highlights an urgent need for therapeutics capable of preventing virus replication.
Olivier Reynard +5 more
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