Results 241 to 250 of about 742,740 (307)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Medicinal attributes of nitrogen heterocycles directing aldose reductase selectivity and potency. [PDF]

RSC Med Chem
Kumari A, Manna SK, Rani K, Kohal R, Gupta GD, Verma SK.   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Pyrimidine nucleoside: inspiration for novel antimicrobial agent. [PDF]

Front Pharmacol
Xu B, Li P, Liu J, Li M.
europepmc   +1 more source

Solid-phase synthesis and biological evaluation of des-hydroxy pseudouridimycin analogs. [PDF]

ACS Med Chem Lett
Anwar AF, You L, Degen D, Burns KJ, Garza MJ, Ebright RH, Del Valle JR.   +6 more
europepmc   +1 more source

Chemical modifications of diphenyl diselenide enhance its anti-Sporothrix spp. activity and exhibit synergism with itraconazole. [PDF]

Braz J Microbiol
Hidalgo JED, Xavier MO, Trápaga MR, Cardoso B, Dos Santos MC, Canary D, Zeni G, Nogueira CW, Almeida-Paes R, Zancopé-Oliveira RM, Poester VR.   +10 more
europepmc   +1 more source

Phenolic Profile, Antioxidant Capacity, Enzyme Inhibitory Potential and Physicochemical Properties of Almond Milk and Date Enriched Plant-Based Ice Cream. [PDF]

Plant Foods Hum Nutr
Hatipoğlu A, Kızmaz V, Çavuşoğlu M.
europepmc   +1 more source