Results 91 to 100 of about 753,617 (295)

Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA [PDF]

open access: yes, 2016
The pathogenesis of malaria is primarily associated with blood-stage infection and there is strong evidence that antibodies specific for parasite blood-stage antigens can control parasitaemia. This provides a strong rationale for incorporation of asexual
Marco Tamborrini (2280460)   +23 more
core   +1 more source

Comparative Analysis of the Inhibitory Efficacy of 50% and 80% Concentrations of Rambutan Seed Extract (Nephelium lappaceum L.) on the Growth of Candida albicans

open access: yesIndonesian Journal of Rheumatology
Introduction. Denture stomatitis is a prevalent issue among those who wear dentures, and it is caused by Candida albicans. Ketoconazole, an azole antifungal medication, is commonly employed to treat denture stomatitis. However, it is important to note that the usage of this agent might lead to hepatotoxicity and the development of resistance.
Cindy Denhara Wijaya   +2 more
openaire   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Inhibitory concentration for 50% reduction in PHE contractile responses (IC50) and Dissociation constants (-KB) values of α1-AR subtypes inhibitors for phenylephrine-induced contractility in ovine middle cerebral arteries.

open access: yes, 2014
Inhibitory concentration for 50% reduction in PHE contractile responses (IC50) and Dissociation constants (-KB) values of α1-AR subtypes inhibitors for phenylephrine-induced contractility in ovine middle cerebral arteries.
Ravi Goyal (499376)   +4 more
core   +1 more source

Evaluation of the effects of diethyl ether and methanol extracts of carpet anemone (Sarcophyton spp.) and starfish (Pentaceraster spp.) on E. coli and Bacillus subtilis bacteria

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2019
Marine environment is the main source of natural bioactive products whose chemical-structural properties are not similar with other natural products of plants and other inland organisms. The present study was carried out to evaluate antibiotic properties
M. Mansurlakuraj; K. Rezaei Tavabe; A.R. Mirvaghefi; M. Nazemi; M.A. Nematollahi; M. Jahandideh
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Half-maximal inhibitory concentration (IC50) values of pyrimidine derivatives MKP106–123 against epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR)-2.

open access: yes, 2015
Half-maximal inhibitory concentration (IC50) values of pyrimidine derivatives MKP106–123 against epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR)-2.
Jiho Song (799714)   +7 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia [PDF]

open access: yes, 2011
The purine adenosine plays an important role in a number of physiological and pathological processes and is neuroprotective during hypoxia and ischemia.
Mark J. Wall   +3 more
core   +1 more source

Antiviral potential of sugarcane bagasse-derived carbon quantum dots against SARS-CoV-2, and herpes simplex virus-1

open access: yesDiscover Applied Sciences
Viral diseases pose a serious global threat due to their ability to spread quickly and mutate. The ongoing SARS-CoV-2 pandemic exemplifies this challenge, as effective treatments and vaccines are still under development.
Hebat-Allah S. Tohamy   +3 more
doaj   +1 more source

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