Results 101 to 110 of about 753,617 (295)

Major Constituents of Resin Exhibit Cyclooxygenase Enzyme Inhibition and Antiproliferative Activity

open access: yesNatural Product Communications, 2013
Aromatic gum from Boswellia carteri (olibanum oleogum) has long been used in Egyptian traditional medicine. Cyclooxygenase-1 (COX-1) enzyme inhibitory assay guided purification of the extracts of this resin resulted in five bioactive compounds, 3α- O ...
Sami I. Ali   +6 more
doaj   +1 more source

A novel chemotherapeutic sensitivity-testing system based on collagen gel droplet embedded 3D–culture methods for hepatocellular carcinoma

open access: yesBMC Cancer, 2017
Background Patients suffering from advanced stage hepatocellular carcinoma (HCC) often exhibit a poor prognosis or dismal clinical outcomes due to ineffective chemotherapy or a multi-drug resistance (MDR) process.
Jun Hou   +13 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Minimal inhibitory concentration of plectasin against clinical isolates of MSSA and MRSA.

open access: yes, 2015
a MIC50 and MIC90 50% and 90% indicate that MIC values at which 50 and 90% of the isolates were inhibited, respectively.Minimal inhibitory concentration of plectasin against clinical isolates of MSSA and MRSA.
James Vaudrey (693517)   +7 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Evaluation of minimum inhibitory concentration of methanol extract of cacao seeds on growth of Streptococcus mutans bacteria by microdilution method

open access: yes, 2023
Background: Indonesia is famous for its medicinal plants. Cocoa bean (Theobroma cacao L.) is a plant widely used as a traditional medicine alternative to cure diseases.
Arifin Ahmad   +12 more
core   +1 more source

The study of antibacterial activity of non-polar extract of Malva silvestris L., using well diffusion and tube dilution method. [PDF]

open access: yesĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2015
Nowadays, due to the resistance of bacteria to antibiotics and their side effects, much attention is paid to the antibacterial properties of medicinal plants. Malva sylvestis L. plays an important role in traditional medicine and herbal medicine industry.
akbar hassanpour   +2 more
doaj  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Inhibitory effects of polysaccharide compounds.

open access: yes, 2013
*Inhibitory concentration 50%: concentration in µg/ml required to inhibit influenza virus plaque formation on MDCK cells. Each value represents the mean of a quadruplicate assay.
Regina Weinmüllner (358845)   +12 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy