Results 121 to 130 of about 753,617 (295)

Half-maximal inhibitory concentration (IC50), half-maximal cytotoxic concentration (CC50), and selectivity index (SI) of PSCD formulation and its ingredients.

open access: yes
Half-maximal inhibitory concentration (IC50), half-maximal cytotoxic concentration (CC50), and selectivity index (SI) of PSCD formulation and its ingredients.
Walaiporn Plirat (17775628)   +5 more
core   +1 more source

Inhibitory and bactericidal power of mangosteen rind extract towards Porphyromonas Gingivalis and Actinobacillus Actinomycetemcomitans (Laboratory test)

open access: yesPadjadjaran Journal of Dentistry, 2016
Introduction: The bacteria that cause the occurrence of pathogens of periodontal disease are gram negative anaerobes. These bacteria include Pophyromonas Gingivalis and Actinobacillus Actinomycetemcomitans.
Ina Hendiani   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

BASIC programs to analyse minimal inhibitory concentration (MIC) antimicrobial susceptibility results

open access: yes, 1988
BASIC programs have been written to analyse minimal inhibitory concentration (MIC) antimicrobial susceptibility results for large numbers of organisms and a wide variety of antimicrobials.
Ling, KLE, French, GL, Ling, J, Chan, KW
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Minimal Inhibitory Concentration (MIC50, MIC90 and range) values of Brucella abortus strains isolated from cattle in Brazil, 1977–2009, to eight antimicrobials used in the treatment of human brucellosis.

open access: yes, 2015
aVariation of MIC values (number of dilution variations) for every antimicrobialbMinimum Inhibitory Concentration required to inhibit the growth of 50% of the strainscMinimum Inhibitory Concentration required to inhibit the growth of 90% of the ...
Juliana Pinto da Silva Mol (771274)   +8 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Cell density and concentrations of AgNPs and FLC used to determine the half–maximal inhibitory concentration (IC50) of fluconazole (FLC) and AgNPs (silver) to inhibit C. albicans.

open access: yes, 2014
The IC50 for each cell concentration is underlined.Cell density and concentrations of AgNPs and FLC used to determine the half–maximal inhibitory concentration (IC50) of fluconazole (FLC) and AgNPs (silver) to inhibit C. albicans.
Miguel Avalos-Borja (468742)   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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